DMWD and PPBP

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		DMWD	PPBP
Description		DM1 locus, WD repeat containing	pro-platelet basic protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Dendrite Cell Projection Perikaryon	Extracellular Region Extracellular Space Platelet Alpha Granule Platelet Alpha Granule Lumen Tertiary Granule Lumen
	Molecular Function	Protein Binding Deubiquitinase Activator Activity	Cytokine Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding D-glucose Transmembrane Transporter Activity
	Biological Process		Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Killing Of Cells Of Another Organism Defense Response To Bacterium Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide D-glucose Transmembrane Transport
Pathways			Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs			Ethanesulfonic acid Copper
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Chronic obstructive pulmonary disease ( 30804561) Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143) Hip circumference ( 28552196) Low density lipoprotein cholesterol levels ( 32154731)	Metabolite levels ( 22916037)
Interacting Genes		2 interacting genes: CCR2 PPBP	32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4
Entrez ID		1762	5473
HPRD ID		13235	07171
Ensembl ID		ENSG00000185800	ENSG00000163736
Uniprot IDs		Q09019 Q8WUW6	P02775
PDB IDs			1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?		Leukocyte Chemotaxis Cell Chemotaxis Myeloid Leukocyte Migration Leukocyte Migration Humoral Immune Response Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Positive Regulation Of Immune Complex Clearance By Monocytes And Macrophages Chemokine (C-C Motif) Ligand 12 Binding Positive Regulation Of Thymocyte Migration Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Chemokine (C-C Motif) Ligand 7 Binding Chemokine (C-C Motif) Ligand 2 Binding Positive Regulation Of Hematopoietic Stem Cell Migration Regulation Of Astrocyte Chemotaxis Chemotaxis Regulation Of Thymocyte Migration Regulation Of Immune Complex Clearance By Monocytes And Macrophages Locomotion CCR2 Chemokine Receptor Binding Positive Regulation Of T Cell Extravasation Positive Regulation Of Monocyte Extravasation Monocyte Extravasation Neutrophil Clearance Inflammatory Response D-glucose Transmembrane Transporter Activity Positive Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Positive Regulation Of Glial Cell Migration Inflammatory Response To Wounding Regulation Of Glutamate Receptor Signaling Pathway CXCR Chemokine Receptor Binding Positive Regulation Of T Cell Chemotaxis Regulation Of Leukocyte Tethering Or Rolling Regulation Of T Cell Chemotaxis Negative Regulation Of Type 2 Immune Response Positive Regulation Of Cellular Extravasation T Cell Chemotaxis Dendritic Cell Chemotaxis Positive Regulation Of T-helper 1 Type Immune Response Cellular Extravasation Platelet Alpha Granule Cell Migration Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Chemokine Receptor Activity Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Lymphocyte Chemotaxis Dendritic Cell Migration	Chemokine Activity Cell Chemotaxis Leukocyte Chemotaxis Chemokine-mediated Signaling Pathway Chemotaxis Locomotion Antimicrobial Humoral Response Granulocyte Chemotaxis Leukocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Granulocyte Migration Humoral Immune Response Cytokine Activity Killing Of Cells Of Another Organism Cell Migration Cytokine-mediated Signaling Pathway Mononuclear Cell Migration Cell Motility Cell Killing CXCR Chemokine Receptor Binding Inflammatory Response Eosinophil Chemotaxis Defense Response To Symbiont Eosinophil Migration Defense Response Defense Response To Other Organism Immune System Process Neutrophil Chemotaxis Immune Response CCR Chemokine Receptor Binding Chemokine Receptor Binding Neutrophil Migration Response To External Biotic Stimulus Response To Other Organism Cell-cell Signaling G Protein-coupled Receptor Signaling Pathway Signaling Cell Communication T Cell Chemotaxis Dendritic Cell Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling CXCR3 Chemokine Receptor Binding Dendritic Cell Migration Lymphocyte Chemotaxis Neutrophil Activation Negative Regulation Of Cellular Extravasation T Cell Migration Positive Regulation Of T Cell Migration Extracellular Space
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