GIMAP1 and ZFYVE27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GIMAP1	ZFYVE27
Description		GTPase, IMAP family member 1	zinc finger FYVE-type containing 27
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane	Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endomembrane System Membrane Axon Dendrite Growth Cone Membrane Cell Projection Recycling Endosome Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process		Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Axon Extension Neurotrophin TRK Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		40 interacting genes: AQP6 ARL13B BLCAP CD79A CLEC10A CPLX4 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FCGR2A GJA8 GPX8 HSD17B11 IL3RA JAGN1 MGST3 PTGES REEP4 RMDN3 SCN3B SLC10A6 SLC14A1 SLC18A1 SLC71A2 STOM STX1A THAP4 TM4SF19 TMEM101 TMEM14B TMEM35A TMEM45B TMEM79 TMX1 TMX2 ZDHHC15 ZFYVE27	18 interacting genes: APP GIMAP1 GIMAP5 IER3IP1 ORMDL1 OTOP3 PIP4P2 SACM1L SEC22A SLC30A8 SLC66A2 STX7 TMEM128 TMEM14C TMEM243 TMEM65 TSPAN2 YIF1A
Entrez ID		170575	118813
HPRD ID		16278	15735
Ensembl ID		ENSG00000213203	ENSG00000155256
Uniprot IDs		A0A090N8Z4 Q8WWP7	A0A0S2Z5V0 A0A0S2Z627 B7Z6J9 Q5T4F4
PDB IDs		3V70	1X4U
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Glutathione Peroxidase Activity Protein Binding Disulfide Oxidoreductase Activity	Membrane Microglia Development Intracellular Transport Vesicle-mediated Transport Insulin Metabolic Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Phosphatidylinositol Dephosphorylation Cellular Localization Endoplasmic Reticulum Establishment Of Localization In Cell SNAP Receptor Activity Golgi Membrane Endoplasmic Reticulum Membrane COPII-coated ER To Golgi Transport Vesicle Phospholipid Dephosphorylation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Endosome Amylin Binding Positive Regulation Of Toll Signaling Pathway
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