GIMAP1 and CLEC10A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GIMAP1	CLEC10A
Description		GTPase, IMAP family member 1	C-type lectin domain containing 10A
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane	Lysosome Lysosomal Membrane Endosome Plasma Membrane External Side Of Plasma Membrane Membrane Early Endosome Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Protein Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity Fucose Binding
	Biological Process		Adaptive Immune Response Immune System Process Endocytosis Immune Response Innate Immune Response
Pathways			Dectin-2 family
Drugs
Diseases
GWAS			Carotid intima media thickness x smoking interaction ( 32117412) GIP levels in response to oral glucose tolerance test (120 minutes) ( 29093273) Liver enzyme levels (alkaline phosphatase) ( 33972514) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		40 interacting genes: AQP6 ARL13B BLCAP CD79A CLEC10A CPLX4 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FCGR2A GJA8 GPX8 HSD17B11 IL3RA JAGN1 MGST3 PTGES REEP4 RMDN3 SCN3B SLC10A6 SLC14A1 SLC18A1 SLC71A2 STOM STX1A THAP4 TM4SF19 TMEM101 TMEM14B TMEM35A TMEM45B TMEM79 TMX1 TMX2 ZDHHC15 ZFYVE27	26 interacting genes: ACSF2 ADIPOQ APOD BET1 C3orf52 CFTR CLN6 FMO3 FXYD6 GIMAP1 MALL NAPB PEX16 PRAF2 SEC22A SLC38A7 SMCO4 SNCA TMEM218 TNF TRARG1 TSPO UNC50 VSTM1 ZDHHC15 ZFPL1
Entrez ID		170575	10462
HPRD ID		16278	12076
Ensembl ID		ENSG00000213203	ENSG00000132514
Uniprot IDs		A0A090N8Z4 Q8WWP7	J3KR22 Q8IUN9
PDB IDs		3V70	6PUV 6PY1 6W12 6XIY
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Glutathione Peroxidase Activity Protein Binding Disulfide Oxidoreductase Activity	Membrane Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Endoplasmic Reticulum Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Peripheral Nervous System Axon Regeneration Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Protein Localization To Membrane Regulation Of Lipid Metabolic Process Negative Regulation Of Secretion Cellular Response To Epinephrine Stimulus Intracellular Protein Localization Positive Regulation Of Monoatomic Ion Transport Response To Epinephrine Regulation Of Chemokine Production Negative Regulation Of Transport Axon Regeneration Establishment Of Protein Localization Regulation Of Oxidative Phosphorylation Regulation Of Smooth Muscle Cell Proliferation Lipid Metabolic Process Glucose Metabolic Process Negative Regulation Of Intracellular Protein Transport Negative Regulation Of Cytokine Production Negative Regulation Of Lipoprotein Lipid Oxidation Neuron Projection Regeneration Regeneration Small Molecule Metabolic Process Regulation Of Hormone Secretion Response To Xenobiotic Stimulus Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Secretion By Cell Positive Regulation Of Transport Negative Regulation Of Secretion By Cell Positive Regulation Of Glial Cell Proliferation Regulation Of Small Molecule Metabolic Process Negative Regulation Of Corticosterone Secretion Negative Regulation Of Lipid Transport Chemical Homeostasis Response To Alcohol Positive Regulation Of Monoatomic Ion Transmembrane Transport Endoplasmic Reticulum Membrane Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Albendazole Monooxygenase Activity Response To Desipramine Regulation Of Aerobic Respiration Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity
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