ZFYVE27 and TMEM243

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZFYVE27	TMEM243
Description		zinc finger FYVE-type containing 27	transmembrane protein 243
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endomembrane System Membrane Axon Dendrite Growth Cone Membrane Cell Projection Recycling Endosome Membrane Endoplasmic Reticulum Tubular Network	Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Axon Extension Neurotrophin TRK Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS			Lung cancer in never smokers ( 28604730) Schizophrenia ( 29483656)
Interacting Genes		18 interacting genes: APP GIMAP1 GIMAP5 IER3IP1 ORMDL1 OTOP3 PIP4P2 SACM1L SEC22A SLC30A8 SLC66A2 STX7 TMEM128 TMEM14C TMEM243 TMEM65 TSPAN2 YIF1A	46 interacting genes: AQP6 BIK CD33 CD74 CD79A CISD2 CLEC14A CPLX4 CREB3 EBP ELOVL4 ELOVL5 ERGIC3 FAM174A FAM209A FFAR2 GJA8 GPR108 GPR152 GPR37L1 GPX8 HSD17B13 JAGN1 KIR2DL3 LIME1 LMNA LRP10 MRM1 MTIF3 MUC1 PLP1 PSCA RETREG3 RMDN3 SAR1A SCN3B SEC11C SLC10A6 SSMEM1 TMEM101 TMEM14B TMEM35A TMEM45B TMEM80 TMPRSS2 ZFYVE27
Entrez ID		118813	79161
HPRD ID		15735	12911
Ensembl ID		ENSG00000155256	ENSG00000135185
Uniprot IDs		A0A0S2Z5V0 A0A0S2Z627 B7Z6J9 Q5T4F4	C9JY04 Q9BU79
PDB IDs		1X4U
Enriched GO Terms of Interacting Partners?		Membrane Microglia Development Intracellular Transport Vesicle-mediated Transport Insulin Metabolic Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Phosphatidylinositol Dephosphorylation Cellular Localization Endoplasmic Reticulum Establishment Of Localization In Cell SNAP Receptor Activity Golgi Membrane Endoplasmic Reticulum Membrane COPII-coated ER To Golgi Transport Vesicle Phospholipid Dephosphorylation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Endosome Amylin Binding Positive Regulation Of Toll Signaling Pathway	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum B Cell Receptor Complex Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Acetylcholine Receptor Regulator Activity Protein Binding Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Negative Regulation Of Peptide Secretion Fatty Acid Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process Endoplasmic Reticulum Organization Fatty Acid Elongation
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