ZFYVE27 and TMEM65

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZFYVE27	TMEM65
Description		zinc finger FYVE-type containing 27	transmembrane protein 65
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endomembrane System Membrane Axon Dendrite Growth Cone Membrane Cell Projection Recycling Endosome Membrane Endoplasmic Reticulum Tubular Network	Nucleolus Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Intercalated Disc Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Axon Extension Neurotrophin TRK Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Protein Localization To Plasma Membrane	Cardiac Ventricle Development Cardiac Conduction Regulation Of Cardiac Conduction
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS			Fear of minor pain ( 28701861)
Interacting Genes		18 interacting genes: APP GIMAP1 GIMAP5 IER3IP1 ORMDL1 OTOP3 PIP4P2 SACM1L SEC22A SLC30A8 SLC66A2 STX7 TMEM128 TMEM14C TMEM243 TMEM65 TSPAN2 YIF1A	33 interacting genes: ABHD16A AQP6 ARL13B CYB561 CYBRD1 EBP ERGIC3 FAM174A FAM209A GJA8 GPR42 HSD17B11 IGSF9 IL3RA JAGN1 JPH1 LMNA MSMO1 PDZK1IP1 PTGES PVR REEP4 RETREG3 SCN3B SLC10A6 SLC18A1 SLC35H1 SLC7A8 TIMMDC1 TMEM101 TMEM80 TMX2 ZFYVE27
Entrez ID		118813	157378
HPRD ID		15735	14102
Ensembl ID		ENSG00000155256	ENSG00000164983
Uniprot IDs		A0A0S2Z5V0 A0A0S2Z627 B7Z6J9 Q5T4F4	Q6PI78
PDB IDs		1X4U
Enriched GO Terms of Interacting Partners?		Membrane Microglia Development Intracellular Transport Vesicle-mediated Transport Insulin Metabolic Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Phosphatidylinositol Dephosphorylation Cellular Localization Endoplasmic Reticulum Establishment Of Localization In Cell SNAP Receptor Activity Golgi Membrane Endoplasmic Reticulum Membrane COPII-coated ER To Golgi Transport Vesicle Phospholipid Dephosphorylation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Endosome Amylin Binding Positive Regulation Of Toll Signaling Pathway	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Ascorbate Homeostasis Transmembrane Monodehydroascorbate Reductase Activity Endoplasmic Reticulum Transmembrane Transport Protein Binding
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