CITED4 and TFAP2C

Number of citations of the paper that reports this interaction (PMID 11744733)
26

Data Source:
HPRD (in vitro)

		CITED4	TFAP2C
Gene Name		Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	Transcription Coactivator Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Dimerization Activity
	Biological Process	Transcription, DNA-templated Response To Estrogen Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Trophectodermal Cell Differentiation Hair Follicle Development Keratinocyte Development Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell-cell Signaling Male Gonad Development Forebrain Neuron Fate Commitment Cerebral Cortex Development Germ-line Stem Cell Maintenance Somatic Stem Cell Maintenance Regulation Of Gene Expression, Epigenetic Regulation Of Cell Proliferation Regulation Of Epidermis Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Sebaceous Gland Development Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: EP300 TFAP2A TFAP2B TFAP2C	10 interactors: CCNG1 CITED1 CITED2 CITED4 GPR22 IKBKB NR1I2 TP53 UBE2I ZFAND4
Entrez ID		163732	7022
HPRD ID		06011	03361
Ensembl ID		ENSG00000179862	ENSG00000087510
Uniprot IDs		Q96RK1	Q92754
PDB IDs
Enriched GO Terms of Interacting Partners?		Tube Development Keratinocyte Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Morphogenesis Skin Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Epithelium Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Sympathetic Nervous System Development Negative Regulation Of RNA Biosynthetic Process Retina Layer Formation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Metanephric Nephron Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Autonomic Nervous System Development Positive Regulation Of Cellular Biosynthetic Process Tissue Development Neural Retina Development Forelimb Morphogenesis Retina Morphogenesis In Camera-type Eye Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Neuron Apoptotic Process Forebrain Neuron Differentiation Positive Regulation Of Neuron Death Negative Regulation Of Cellular Metabolic Process Forebrain Generation Of Neurons Tissue Morphogenesis Keratinocyte Differentiation Nervous System Development Transcription, DNA-templated RNA Biosynthetic Process Anatomical Structure Morphogenesis Metanephros Development Chordate Embryonic Development Positive Regulation Of Cellular Metabolic Process Embryo Development Ending In Birth Or Egg Hatching Histone H2B Acetylation Optic Cup Structural Organization Cellular Creatinine Homeostasis Cellular Urea Homeostasis Cellular Ammonia Homeostasis Camera-type Eye Morphogenesis Cardiovascular System Development Transcription From RNA Polymerase II Promoter Epidermal Cell Differentiation	Response To Organic Substance Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Response To Hormone Negative Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Response To Steroid Hormone Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Signal Transduction Negative Regulation Of Gene Expression Response To Estrogen Negative Regulation Of Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Regulation Of Transcription, DNA-templated Response To Lipid Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Drug Export Response To Interleukin-11 Positive Regulation Of SUMO Transferase Activity Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Pattern Specification Process Cellular Response To Hypoxia Regulation Of Metabolic Process Cellular Response To Decreased Oxygen Levels Embryonic Organ Development Transcription, DNA-templated Negative Regulation Of Macromitophagy
Tagcloud ?		acetylation acetyltransferase antagonized cbp deacetylases deleted docked dramatic effectors erk1 follicles gcs granulosa h2b hdacs indispensable lh luteinizing lys5 lys9 modulating ordered ovulation ovulatory pituitary proposition rapid triggering turn	achieved additionally basal biopsy breast cd44 chemotherapy cluster cores immunohistochemistry luminal mb mda neoadjuvant overexpression pathologic pcr plasmid predictive pretreatment receiving regulates repressed represses residual specimens stained tumors
Tagcloud (Difference) ?		acetylation acetyltransferase antagonized cbp deacetylases deleted docked dramatic effectors erk1 follicles gcs granulosa h2b hdacs indispensable lh luteinizing lys5 lys9 modulating ordered ovulation ovulatory pituitary proposition rapid triggering turn	achieved additionally basal biopsy breast cd44 chemotherapy cluster cores immunohistochemistry luminal mb mda neoadjuvant overexpression pathologic pcr plasmid predictive pretreatment receiving regulates repressed represses residual specimens stained tumors
Tagcloud (Intersection) ?