RIBC1 and ATP6V0D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RIBC1	ATP6V0D2
Description		RIB43A domain with coiled-coils 1	ATPase H+ transporting V0 subunit d2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Lysosomal Membrane Endosome Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Flagellated Sperm Motility	Monoatomic Ion Transport Vacuolar Transport Vacuolar Acidification Regulation Of Macroautophagy Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Bipolar disorder ( 31043756)	Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		25 interacting genes: ATP6V0D2 BORCS6 CCNC EMILIN1 GOLGA2 GPSM1 HSF2BP KRT15 KRT31 KRT36 LDOC1 MISP MKRN3 MPPED2 OIP5 PFDN5 RINT1 TBC1D21 TEX11 TLE5 TOX2 TRIM23 TRIM27 USHBP1 VPS37C	20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474
Entrez ID		158787	245972
HPRD ID		06553	16522
Ensembl ID		ENSG00000158423	ENSG00000147614
Uniprot IDs		Q8N443	Q8N8Y2
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Regulation Of Autophagy Establishment Of Localization In Cell Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Organization Identical Protein Binding Supramolecular Fiber Organization	NF-kappaB Complex DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Nucleus Nucleoplasm Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II
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