STOML3 and ADAM33

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STOML3	ADAM33
Description		stomatin like 3	ADAM metallopeptidase domain 33
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Neuron Projection Membrane Raft	Membrane
	Molecular Function	Protein Binding Ion Channel Inhibitor Activity	Metalloendopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Signal Transduction	Proteolysis
Pathways		Stimuli-sensing channels	Regulation of CDH11 function
Drugs
Diseases			Asthma
GWAS		Daytime sleep phenotypes ( 27126917) Metabolic syndrome ( 20694148)	Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: ADAM33 ADCY3 APP CAV1 CLDN19 JAGN1 SEC22A UPK2 ZDHHC24	33 interacting genes: AQP9 ASGR2 ATXN7 BTNL9 CD3E CLDN2 CLEC7A CREB3L1 CYB5R3 EPGN FCGR2A GGT6 HIBADH KIR3DL3 LMNA MUC1 NCR1 OPRM1 PLEKHO1 SEC11A SGCB SLC22A23 SLC30A2 SLC35E2A SLC4A1 SPINT1 STOML3 TMEM106C TMEM14B TMEM237 TNFSF14 UBQLN4 VMA21
Entrez ID		161003	80332
HPRD ID		16315	06173
Ensembl ID		ENSG00000133115	ENSG00000149451
Uniprot IDs		Q8TAV4	A2A2L3 Q9BZ11
PDB IDs			1R54 1R55
Enriched GO Terms of Interacting Partners?		Peptidase Activator Activity Membrane Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Defense Response To Fungus Response To Fungus Endoplasmic Reticulum Regulation Of Nitric Oxide Metabolic Process Inward Rectifier Potassium Channel Inhibitor Activity Olfactory Learning Associative Learning Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Membrane Potential Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Insulin Receptor Internalization Protein Localization To Basolateral Plasma Membrane Intracellular Nitric Oxide Homeostasis Nitric-oxide Synthase Inhibitor Activity Caveolar Macromolecular Signaling Complex Mesaxon Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Calcium Ion Transmembrane Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Vesicle-mediated Transport Astrocyte Activation Involved In Immune Response	Membrane Plasma Membrane
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