STOML3 and ADCY3

Number of citations of the paper that reports this interaction (PMID 12122055)
4

Data Source:
HPRD (in vivo)

		STOML3	ADCY3
Gene Name		stomatin (EPB72)-like 3	adenylate cyclase 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Plasma Membrane Cilium Integral Component Of Membrane Membrane Raft	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cilium Membrane
	Molecular Function	Molecular_function	Adenylate Cyclase Activity Calmodulin Binding ATP Binding Metal Ion Binding
	Biological Process	Signal Transduction Biological_process	Renal Water Homeostasis Energy Reserve Metabolic Process CAMP Biosynthetic Process Water Transport Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Synaptic Transmission Sensory Perception Of Smell Fibroblast Growth Factor Receptor Signaling Pathway Activation Of Protein Kinase A Activity Intracellular Signal Transduction Small Molecule Metabolic Process Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Transmembrane Transport Cellular Response To Glucagon Stimulus
Pathways			Signaling by GPCR Ca-dependent events CaM pathway Hedgehog 'off' state Phospholipase C-mediated cascade Signaling by FGFR in disease Integration of energy metabolism Activation of GABAB receptors G alpha (s) signalling events Signaling by EGFRvIII in Cancer Adenylate cyclase activating pathway PLCG1 events in ERBB2 signaling DAP12 signaling G alpha (z) signalling events G alpha (i) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Glucagon signaling in metabolic regulation Signaling by PDGF Calmodulin induced events DAP12 interactions PKA-mediated phosphorylation of CREB Opioid Signalling PKA activation Aquaporin-mediated transport CREB phosphorylation through the activation of Adenylate Cyclase EGFR interacts with phospholipase C-gamma Signaling by ERBB2 Signaling by EGFR PKA-mediated phosphorylation of CREB GPCR downstream signaling Calmodulin induced events Downstream signal transduction Signaling by EGFR in Cancer PKA activation Transmission across Chemical Synapses DAG and IP3 signaling CaM pathway Activation of NMDA receptor upon glutamate binding and postsynaptic events Downstream signaling of activated FGFR Post NMDA receptor activation events Innate Immune System GABA B receptor activation GABA receptor activation Adenylate cyclase inhibitory pathway PKA activation in glucagon signalling Signalling by NGF PLC beta mediated events Vasopressin regulates renal water homeostasis via Aquaporins Signaling by Ligand-Responsive EGFR Variants in Cancer G-protein mediated events NGF signalling via TRKA from the plasma membrane Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by FGFR Inhibition of adenylate cyclase pathway Adenylate cyclase inhibitory pathway Signaling by Hedgehog PLC-gamma1 signalling
Drugs
Diseases
GWAS		Metabolic syndrome ( 20694148)	Body mass index ( 22344219 20935630 23583978) Body mass index (non-asthmatics) ( 23517042) Height ( 23563607 18391951) Inflammatory bowel disease ( 23128233) Obesity ( 23563607) Pubertal anthropometrics ( 23449627) Type 1 diabetes ( 21980299)
Protein-Protein Interactions		3 interactors: ADCY3 APP CAV1	2 interactors: CAMK2G STOML3
Entrez ID		161003	109
HPRD ID		16315	02620
Ensembl ID		ENSG00000133115	ENSG00000138031
Uniprot IDs		Q8TAV4	B3KT86 O60266
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Body Fluid Levels Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Chemical Homeostasis Positive Regulation Of Hydrolase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Peptidase Activity Regulation Of Protein Binding Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Homeostatic Process Regulation Of Peptidyl-tyrosine Phosphorylation Synaptic Growth At Neuromuscular Junction Nitric Oxide Homeostasis Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Collateral Sprouting In Absence Of Injury Regulation Of Inward Rectifier Potassium Channel Activity Regulation Of Binding Cellular Calcium Ion Homeostasis Positive Regulation Of Proteolysis Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Calcium Ion Homeostasis Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Collateral Sprouting Axon Midline Choice Point Recognition Mammary Gland Involution Regulation Of Cellular Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Protein Localization To Plasma Membrane Raft Immune System Process Axon Choice Point Recognition Positive Regulation Of Metalloenzyme Activity Caveola Assembly Regulation Of Protein Metabolic Process Regulation Of Cellular Amino Acid Metabolic Process Cellular Metal Ion Homeostasis Regulation Of Peptidase Activity Regulation Of Cardiac Muscle Cell Action Potential Regulation Of The Force Of Heart Contraction By Chemical Signal Blood Coagulation Hemostasis	Regulation Of Relaxation Of Cardiac Muscle Regulation Of Relaxation Of Muscle Regulation Of Skeletal Muscle Adaptation
Tagcloud ?			angptl2 annotated beadchip bmi boston boys c18orf8 corrected correction cpg dok2 epigenomic fdr generational humanmethylation27 illumina infant lends maternal mother offspring plac1 prepregnancy prr16 sapcd2 separately stated wnt16 zcchc10
Tagcloud (Difference) ?			angptl2 annotated beadchip bmi boston boys c18orf8 corrected correction cpg dok2 epigenomic fdr generational humanmethylation27 illumina infant lends maternal mother offspring plac1 prepregnancy prr16 sapcd2 separately stated wnt16 zcchc10
Tagcloud (Intersection) ?