ADAM33 and BTNL9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ADAM33	BTNL9
Description		ADAM metallopeptidase domain 33	butyrophilin like 9
Image			No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Metalloendopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Proteolysis	Regulation Of Cytokine Production T Cell Receptor Signaling Pathway
Pathways		Regulation of CDH11 function	Butyrophilin (BTN) family interactions
Drugs
Diseases		Asthma
GWAS		Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494) Reticulocyte count ( 32888494) White blood cell count ( 32888494)	Metabolite levels ( 23823483)
Interacting Genes		33 interacting genes: AQP9 ASGR2 ATXN7 BTNL9 CD3E CLDN2 CLEC7A CREB3L1 CYB5R3 EPGN FCGR2A GGT6 HIBADH KIR3DL3 LMNA MUC1 NCR1 OPRM1 PLEKHO1 SEC11A SGCB SLC22A23 SLC30A2 SLC35E2A SLC4A1 SPINT1 STOML3 TMEM106C TMEM14B TMEM237 TNFSF14 UBQLN4 VMA21	16 interacting genes: ADAM33 ADIPOQ CXCL9 CYB5B EDDM3A GIMAP5 JAGN1 NINJ2 PLPP6 RPRM SLC38A7 SLC61A1 SMIM3 SYS1 TNF UPK2
Entrez ID		80332	153579
HPRD ID		06173	12550
Ensembl ID		ENSG00000149451	ENSG00000165810
Uniprot IDs		A2A2L3 Q9BZ11	A0A1S5UZ21 Q6UXG8 Q8N324
PDB IDs		1R54 1R55
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane	Positive Regulation Of Neutrophil Activation Regulation Of Neutrophil Activation Cytokine-mediated Signaling Pathway Membrane Negative Regulation Of Bile Acid Secretion Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Protein Localization To Plasma Membrane Response To Gram-negative Bacterium Negative Regulation Of Secretion Negative Regulation Of Branching Involved In Lung Morphogenesis Response To Monosaccharide Response To Carbohydrate Negative Regulation Of Blood Pressure Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Sperm Displacement L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Cytokine Activity Leukocyte Migration Neutrophil Migration Regulation Of Hormone Secretion Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Protein Localization To Cell Periphery Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Interleukin-8 Production Positive Regulation Of Fractalkine Production Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Regulation Of D-glucose Import Positive Regulation Of Vitamin D Biosynthetic Process Negative Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Detection Of Oxidative Stress Negative Regulation Of Hormone Secretion Positive Regulation Of Chemokine Production Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Response To Other Organism
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