RBMY1F and AEN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RBMY1F	AEN
Description		RNA binding motif protein Y-linked family 1 member F	apoptosis enhancing nuclease
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus	Nucleus Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding	Nucleic Acid Binding Nuclease Activity Exonuclease Activity DNA Exonuclease Activity Protein Binding Hydrolase Activity
	Biological Process	MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome	DNA Metabolic Process RNA Processing Apoptotic Process DNA Damage Response Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS			Dupuytren's disease ( 28886342) Night sleep phenotypes ( 27126917)
Interacting Genes		35 interacting genes: AEN APOBEC3C CBX2 CIRBP CLK3 CNNM3 DAAM2 EPM2AIP1 HHEX HNRNPK LNX1 NPDC1 PCDHB14 PPP1R37 PRPF31 PRR3 RAMAC RASD1 RBM10 RBM3 RBMX RBMY1A1 RBMY1E RBMY1J RNPS1 SNRPA SPATC1L TRA2B U2AF2 YTHDC1 ZNF317 ZNF385C ZNF408 ZNF792 ZNF837	36 interacting genes: EMD EXOSC8 GNPTAB HAP1 HOMEZ IKZF1 KANK2 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SPOP SSX2IP TLE5 TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF408 ZNF473
Entrez ID		159163	64782
HPRD ID		15232	08573
Ensembl ID		ENSG00000169800	ENSG00000181026
Uniprot IDs		J3KQ82 Q15415	Q8WTP8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing Positive Regulation Of RNA Splicing Spliceosomal Complex Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process MRNA Processing Nucleic Acid Binding RNA Splicing RNA Processing MRNA Metabolic Process RNA Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Metabolic Process RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Nucleus Nucleic Acid Metabolic Process Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Binding Nuclear Speck Protein Binding Negative Regulation Of Gene Expression Regulation Of Metabolic Process Nucleoplasm Negative Regulation Of Macromolecule Biosynthetic Process Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Biosynthetic Process Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Ribosomal Large Subunit Export From Nucleus Ribonucleoprotein Complex Localization U4/U6 X U5 Tri-snRNP Complex	Keratin Filament Intermediate Filament Identical Protein Binding Nucleus Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Zinc Ion Binding Regulation Of RNA Splicing Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Regulation Of Macromolecule Biosynthetic Process
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