Wiki-Pi
About
Search
People
Updates
Search
ZDHHC15 and BNIP3
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
ZDHHC15
BNIP3
Description
zDHHC palmitoyltransferase 15
BCL2 interacting protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum
Golgi Apparatus
Postsynaptic Density
Membrane
Synapse
Postsynapse
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Envelope
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Postsynaptic Density
Membrane
Dendrite
Mitochondrial Membrane
Molecular Function
Protein Binding
Zinc Ion Binding
Palmitoyltransferase Activity
Transferase Activity
Acyltransferase Activity
Protein-cysteine S-myristoyltransferase Activity
Protein-cysteine S-palmitoyltransferase Activity
Metal Ion Binding
Protein-cysteine S-stearoyltransferase Activity
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
GTPase Binding
Endoplasmic Reticulum-autophagosome Adaptor Activity
Mitochondrion Autophagosome Adaptor Activity
Biological Process
Protein Targeting To Membrane
Synaptic Vesicle Maturation
Peptidyl-L-cysteine S-palmitoylation
Establishment Of Protein Localization
Regulation Of Dendritic Spine Morphogenesis
Protein Localization To Postsynapse
Protein Localization To Membrane
Protein Targeting To Golgi Apparatus
Positive Regulation Of Dendrite Development
Autophagy Of Mitochondrion
Mitophagy
Response To Hypoxia
Apoptotic Process
Response To Bacterium
Positive Regulation Of Autophagy
Negative Regulation Of Mitochondrial Fusion
Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Mitochondrial Membrane Potential
Positive Regulation Of Macroautophagy
Cerebral Cortex Development
Mitochondrial Protein Catabolic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Protein-containing Complex Disassembly
Mitochondrial Fragmentation Involved In Apoptotic Process
Negative Regulation Of Membrane Potential
Regulation Of Mitochondrial Membrane Permeability
Autophagic Cell Death
Response To Axon Injury
Oligodendrocyte Differentiation
Brown Fat Cell Differentiation
Neuron Apoptotic Process
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Defense Response To Virus
Response To Hyperoxia
Reticulophagy
Substrate Localization To Autophagosome
Cellular Response To Hydrogen Peroxide
Cellular Response To Mechanical Stimulus
Cellular Response To Cobalt Ion
Cellular Response To Hypoxia
Reactive Oxygen Species Metabolic Process
Positive Regulation Of Mitochondrial Fission
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Response To Oxygen-glucose Deprivation
Intrinsic Apoptotic Signaling Pathway
Mitochondrial Outer Membrane Permeabilization
Granzyme-mediated Programmed Cell Death Signaling Pathway
Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Positive Regulation Of Autophagy Of Mitochondrion
Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia
Pathways
Drugs
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Metabolite levels (
23823483
)
Interacting Genes
49 interacting genes:
ADCYAP1R1
ARL13B
BNIP3
C14orf180
CD79A
CELA2B
CERCAM
CFTR
CLEC10A
CLRN1
CREB3L1
CYB5R3
DHRSX
ERGIC3
FAM241B
GIMAP1
GOLGA7B
GPR152
LEMD1
LEPROTL1
LHFPL5
LMNA
LSMEM1
MCEMP1
MTIF3
ORMDL1
ORMDL2
PEX16
PLLP
PRAF2
PVR
RUSF1
SLC10A6
SMIM1
SNORC
STX3
TBXA2R
TMEFF2
TMEM120B
TMEM128
TMEM14C
TMEM222
TMEM42
TMEM52B
TNFRSF10B
TSNARE1
TUFM
VAPB
YIPF4
71 interacting genes:
AGTR1
AMIGO1
ARL13B
BCL2
BCL2L1
BCL2L2
BIK
BNIP2
BNIP3L
CD3E
CD47
CLDN9
CLEC7A
CLN8
CMTM5
CREB3
CREB3L1
EBAG9
EBP
ELOVL4
ERGIC3
FAM209A
FAM241B
FATE1
FBXL4
FFAR2
FXYD6-FXYD2
GPR152
GPR37
GPR42
HIF1A
HIVEP1
HPN
HTR2B
IFNGR2
JAGN1
KTN1
LDLRAD1
LMNA
MALL
MAP1LC3B
MS4A3
NCBP1
OPA1
PLP2
PPTC7
REEP2
RHEB
RNASEK
RNF24
RPRM
SCN3B
SEC22A
SEC23A
SLC31A2
SLC35B1
SLC6A17
SLC71A2
SMIM3
SPACA1
TGM2
TLCD4
TM4SF18
TMEM101
TMEM106C
TMEM11
TMEM205
TMPRSS2
TMX2
TNMD
ZDHHC15
Entrez ID
158866
664
HPRD ID
06758
04482
Ensembl ID
ENSG00000102383
ENSG00000176171
Uniprot IDs
B3KY34
Q96MV8
Q12983
Q6NVY4
PDB IDs
2J5D
2KA1
2KA2
Enriched GO Terms of Interacting Partners
?
Membrane
Membrane Docking
Organelle Localization By Membrane Tethering
Intracellular Sphingolipid Homeostasis
Negative Regulation Of Ceramide Biosynthetic Process
Protein Binding
Negative Regulation Of Sphingolipid Biosynthetic Process
Serine Palmitoyltransferase Complex
Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Bcl-2 Family Protein Complex
Protein Binding
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Mitochondrial Outer Membrane
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Mitochondrial Membrane Organization
Apoptotic Mitochondrial Changes
Negative Regulation Of Apoptotic Process
Mitochondrial Membrane
Mitochondrion Organization
Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Programmed Cell Death
Regulation Of Release Of Cytochrome C From Mitochondria
Dendritic Cell Apoptotic Process
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Negative Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Apoptotic Process
Golgi Membrane
Negative Regulation Of Autophagy
Regulation Of Programmed Cell Death
Release Of Cytochrome C From Mitochondria
Regulation Of Intrinsic Apoptotic Signaling Pathway
BH3 Domain Binding
Apoptotic Process
Membrane Organization
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Programmed Cell Death
Cell Death
Positive Regulation Of Cell Maturation
Negative Regulation Of Dendritic Cell Apoptotic Process
Channel Activity
Regulation Of Response To Endoplasmic Reticulum Stress
Ceramide Binding
Transmembrane Transport
Chemical Homeostasis
Mitochondrion
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?