ZDHHC15 and CERCAM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZDHHC15	CERCAM
Description		zDHHC palmitoyltransferase 15	cerebral endothelial cell adhesion molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Postsynaptic Density Membrane Synapse Postsynapse	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Plasma Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Metal Ion Binding Protein-cysteine S-stearoyltransferase Activity	Protein Binding Identical Protein Binding Procollagen Galactosyltransferase Activity
	Biological Process	Protein Targeting To Membrane Synaptic Vesicle Maturation Peptidyl-L-cysteine S-palmitoylation Establishment Of Protein Localization Regulation Of Dendritic Spine Morphogenesis Protein Localization To Postsynapse Protein Localization To Membrane Protein Targeting To Golgi Apparatus Positive Regulation Of Dendrite Development	Cell Adhesion Leukocyte Cell-cell Adhesion
Pathways
Drugs
Diseases		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS			Body mass index ( 26426971) Systemic lupus erythematosus ( 26606652)
Interacting Genes		49 interacting genes: ADCYAP1R1 ARL13B BNIP3 C14orf180 CD79A CELA2B CERCAM CFTR CLEC10A CLRN1 CREB3L1 CYB5R3 DHRSX ERGIC3 FAM241B GIMAP1 GOLGA7B GPR152 LEMD1 LEPROTL1 LHFPL5 LMNA LSMEM1 MCEMP1 MTIF3 ORMDL1 ORMDL2 PEX16 PLLP PRAF2 PVR RUSF1 SLC10A6 SMIM1 SNORC STX3 TBXA2R TMEFF2 TMEM120B TMEM128 TMEM14C TMEM222 TMEM42 TMEM52B TNFRSF10B TSNARE1 TUFM VAPB YIPF4	38 interacting genes: ABHD5 ATG9A CDC23 CREB5 CYSRT1 DSCR9 FANCL FKBP7 FNDC11 GEMIN4 GLRX3 GOPC HOXA1 KLHL38 KRTAP15-1 KRTAP26-1 KRTAP3-3 KRTAP6-2 KRTAP8-1 KRTAP9-3 LASP1 LCOR MAGED1 MKRN3 OTX1 P4HA3 POGZ POU4F2 RBM11 RHOXF2 RUNX1 SFT2D1 SOHLH1 TENT5B UBL5 VENTX VGLL3 ZDHHC15
Entrez ID		158866	51148
HPRD ID		06758	16705
Ensembl ID		ENSG00000102383	ENSG00000167123
Uniprot IDs		B3KY34 Q96MV8	Q5T4B2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Membrane Docking Organelle Localization By Membrane Tethering Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Protein Binding Negative Regulation Of Sphingolipid Biosynthetic Process Serine Palmitoyltransferase Complex	Intermediate Filament Chromatin
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