CDK18 and CCDC102B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CDK18	CCDC102B
Description		cyclin dependent kinase 18	coiled-coil domain containing 102B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Cytoplasm Centriole Cytoskeleton
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Protein Binding Protein Serine/threonine Kinase Binding
	Biological Process	Positive Regulation Of Myelination Regulation Of Cell Cycle Phase Transition	Centriole-centriole Cohesion
Pathways
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 29695241)	Caudate activity during reward ( 28927378) Liver enzyme levels (alanine transaminase) ( 24124411) Myopic maculopathy ( 29725004) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Rostral anterior cingulate cortex volume ( 31530798)
Interacting Genes		55 interacting genes: AK8 APP BLZF1 CBY2 CCDC102B CCDC125 CCDC85B CCDC88B CCND3 CCNDBP1 CCNK CEP76 EYA2 FSD2 GOLGA2 GOLGA6L9 GORASP2 HAP1 HMBOX1 HOMER3 HOOK2 INCA1 KIFC3 KRT15 KRT16 KRT31 KRT34 KRT40 KRT75 KRT86 LZTS2 MAD1L1 MID2 MIPOL1 MTUS2 NUTM1 PIBF1 PNMA1 PPFIA1 RABEP1 REL SEC23A TRAF1 TRAF2 TRIM27 TRIM50 TRIM54 TSGA10 TTC23 VPS28 VPS52 ZNF426 ZNF438 ZNF774 ZRANB1	102 interacting genes: ABI2 AK8 ANKRD23 ARL4A ARL4D BYSL C20orf202 CACNB4 CAPN3 CCDC120 CCDC187 CCDC33 CCHCR1 CDK18 CEP19 CEP57L1 CWF19L2 DISC1 DOCK10 EFHC2 EHHADH ENKD1 EXOC5 FAM161A FAM217B FBF1 FH FLOT1 FNDC11 GEM GOPC HMG20B IKZF3 KIFC3 KPNA3 KRT75 KRTAP13-3 LENG1 LMO4 LNX1 LZTS1 MAB21L2 MAGOHB MARK1 MCM7 MEOX1 MEOX2 MFAP1 MOS MSX2 NIF3L1 NME4 NTAQ1 NXT2 PFKFB4 PHAF1 PICK1 PNMA5 POMC POP5 PPP1R13B PPP1R18 PRPF18 PSMA1 RASAL3 RCOR3 RSPH14 RTL8A RTL8B RTL8C SDCBP SFN SGF29 SH3RF2 SLIRP SMARCD1 SNAPIN SORBS3 SPATA18 SPATA2 SPG21 SYCE1 SYT17 TCEANC TCP10L TFIP11 TNNI1 TPM3 TRIM27 TRIM54 TSGA10IP TTC23 VPS52 ZBTB32 ZBTB42 ZC2HC1C ZNF20 ZNF250 ZNF572 ZNF620 ZNF688 ZNF774
Entrez ID		5129	79839
HPRD ID		01354	08038
Ensembl ID		ENSG00000117266	ENSG00000150636
Uniprot IDs		Q07002 Q59G02	Q68D86
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Supramolecular Fiber Organization Intermediate Filament Cytoskeleton Organization Centrosome Microtubule Protein Binding Microtubule Binding Cytoplasm Structural Molecule Activity Organelle Organization Microtubule-based Process Dynein Light Intermediate Chain Binding Identical Protein Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Cytosol Cellular Localization Thioesterase Binding Cis-Golgi Network Golgi Organization Cyclin-dependent Protein Serine/threonine Kinase Activator Activity	Protein Binding
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