ALKBH3

Gene Name		alkB, alkylation repair homolog 3 (E. coli)
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion
	Molecular Function	Protein Binding Ferrous Iron Binding L-ascorbic Acid Binding DNA-N1-methyladenine Dioxygenase Activity Cytosine C-5 DNA Demethylase Activity
	Biological Process	DNA Repair DNA Dealkylation Involved In DNA Repair Cell Proliferation Oxidative Single-stranded DNA Demethylation
Pathways		ABH3 mediated Reversal of Alkylation Damage DNA Damage Reversal Reversal of Alkylation Damage By DNA Dioxygenases
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: AK8 GLRX3 GOLGA2 IKZF1 LNX1 SRPK1 SRPK2 ZDHHC17
Entrez ID		221120
HPRD ID		16793
Ensembl ID		ENSG00000166199
Uniprot IDs		Q96Q83
PDB IDs		2IUW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Positive Regulation Of Neutrophil Differentiation Nuclear Speck Organization Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleus Organization Regulation Of Viral Process Positive Regulation Of NK T Cell Differentiation Positive Regulation Of Granulocyte Differentiation Sperm Chromatin Condensation Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Muscle Hypertrophy
Tagcloud ?		2og alkyl chromatin comprised demethylase dioxygenase display fe fto hits homologs hybrid interact marginally mediating modification oxoglutarate partners possess repairs rest reversal screens