CCDC167 and TMEM80

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC167	TMEM80
Description		coiled-coil domain containing 167	transmembrane protein 80
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Cilium Membrane Ciliary Transition Zone Cell Projection
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Non-motile Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Restless legs syndrome ( 29029846) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		46 interacting genes: APPBP2 AQP2 AQP6 AQP9 ARL13B CD79A CFTR CLDN5 CX3CR1 EBP ELOVL4 ERGIC3 FAM174A FAM210B FFAR2 FOXP1 GJA8 GLP1R GOLT1A GPR152 GPR42 GPX8 HSD17B13 MS4A3 MTNR1A MUC1 NIPA1 OPRM1 RETREG3 SCN3B SERINC2 SLC10A6 SLC18A3 SLC35H1 SLC7A14 SYT2 TACR1 TLCD4 TM4SF19 TMEM179B TMEM237 TMEM51 TMEM80 TMEM86B TMX2 VKORC1	65 interacting genes: ADGRE2 AGTR1 AIG1 AQP1 ARL6IP6 BET1 BIK C11orf24 C14orf180 C3orf52 C5orf46 CCDC167 CD63 CLDN11 CLDN19 CLDN8 CLDND2 CLEC2D CMTM5 CNIH3 COL4A5 CXCR2 CYBC1 DOLK EMD ERMP1 FAM20B FAM3C FKBP8 FXYD3 GPR37L1 IER3IP1 LAT LSMEM1 MALL MRAP2 NKG7 PRB1 PTPN9 PTPRN RPRM SERP2 SLC30A8 SLC66A2 SMAGP SMCO4 STATH STX7 SYNGR1 TLCD1 TMEM100 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14A TMEM243 TMEM65 TNFRSF10C TRARG1 TSPAN1 TSPO2 TVP23B VKORC1L1 WNT4
Entrez ID		154467	283232
HPRD ID		18561	14143
Ensembl ID		ENSG00000198937	ENSG00000177042
Uniprot IDs		Q9P0B6	A0A0A0MTU4 A0AAA9X375 E9PQJ9 Q96HE8
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Water Transport Fluid Transport Transmembrane Transport Water Channel Activity G Protein-coupled Receptor Activity Plasma Membrane Organic Hydroxy Compound Transport Glycerol Transmembrane Transport G Protein-coupled Peptide Receptor Activity Positive Regulation Of Synaptic Transmission, Cholinergic Channel Activity Renal Water Transport Protein Binding Polyol Transmembrane Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Endoplasmic Reticulum	Membrane Plasma Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein Binding
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