CCDC167 and SLC18A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC167	SLC18A3
Description		coiled-coil domain containing 167	solute carrier family 18 member A3
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Membrane AP-1 Adaptor Complex AP-2 Adaptor Complex Clathrin-coated Endocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Terminal Bouton Synapse Clathrin-sculpted Acetylcholine Transport Vesicle Membrane
	Molecular Function	Protein Binding	Acetylcholine Transmembrane Transporter Activity Acetylcholine:proton Antiporter Activity Protein Binding Monoamine:proton Antiporter Activity Transmembrane Transporter Activity
	Biological Process		Neurotransmitter Transport Chemical Synaptic Transmission Positive Regulation Of Acetylcholine Secretion, Neurotransmission Serotonin Uptake Acetylcholine Uptake Transmembrane Transport Positive Regulation Of Long-term Synaptic Potentiation Proton Transmembrane Transport Positive Regulation Of Neuromuscular Junction Development
Pathways			Acetylcholine Neurotransmitter Release Cycle Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Restless legs syndrome ( 29029846) Smoking status (ever vs never smokers) ( 30643258)	Asthma (childhood onset) ( 31036433)
Interacting Genes		46 interacting genes: APPBP2 AQP2 AQP6 AQP9 ARL13B CD79A CFTR CLDN5 CX3CR1 EBP ELOVL4 ERGIC3 FAM174A FAM210B FFAR2 FOXP1 GJA8 GLP1R GOLT1A GPR152 GPR42 GPX8 HSD17B13 MS4A3 MTNR1A MUC1 NIPA1 OPRM1 RETREG3 SCN3B SERINC2 SLC10A6 SLC18A3 SLC35H1 SLC7A14 SYT2 TACR1 TLCD4 TM4SF19 TMEM179B TMEM237 TMEM51 TMEM80 TMEM86B TMX2 VKORC1	3 interacting genes: CCDC167 MFF PEDS1-UBE2V1
Entrez ID		154467	6572
HPRD ID		18561	08979
Ensembl ID		ENSG00000198937	ENSG00000187714
Uniprot IDs		Q9P0B6	Q16572
PDB IDs			8XTW 8XTX 8XTY 8ZMR 8ZMS
Enriched GO Terms of Interacting Partners?		Membrane Water Transport Fluid Transport Transmembrane Transport Water Channel Activity G Protein-coupled Receptor Activity Plasma Membrane Organic Hydroxy Compound Transport Glycerol Transmembrane Transport G Protein-coupled Peptide Receptor Activity Positive Regulation Of Synaptic Transmission, Cholinergic Channel Activity Renal Water Transport Protein Binding Polyol Transmembrane Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Endoplasmic Reticulum	Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Fission Protein Targeting To Mitochondrion Peroxisome Fission Mitochondrial Fission
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