KRTAP10-10 and CSNK1G3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP10-10	CSNK1G3
Description		keratin associated protein 10-10	casein kinase 1 gamma 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process		Endocytosis Signal Transduction Wnt Signaling Pathway Protein Modification Process Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Keratinization
Drugs			Purvalanol A {4-Amino-2-[(4-methoxyphenyl)amino]-1,3-thiazol-5-yl}(4-methoxyphenyl)methanone 4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium K-00546
Diseases
GWAS			Adult asthma ( 27611488) Amyotrophic lateral sclerosis ( 19451621) Apolipoprotein B levels ( 32203549) Cholesterol, total ( 24097068) Chronotype ( 30696823) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Diastolic blood pressure ( 30578418 27618452) Heel bone mineral density ( 30598549 28869591) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 28334899 32203549) Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels ( 23823483) Nickel levels ( 26025379) Pulse pressure ( 27618448) Rapid response to perioperative phenylephrine (change in systolic blood pressure) ( 33168928) Red cell distribution width ( 32888494) Systolic blood pressure ( 27618452) Total body bone mineral density ( 29304378) Total cholesterol levels ( 28334899) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)
Interacting Genes		26 interacting genes: AXIN2 CATSPER1 CREB5 CSNK1G3 CTSZ CYSRT1 HOXA1 KRTAP10-8 KRTAP4-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-3 LCE1B LCE1C LCE1E LCE1F LCE2C LCE3B LCE3C NBPF19 NDUFB7 NOTCH2NLA PLEKHF2 ZNF473 ZNF587	7 interacting genes: CLSPN DBNDD2 DRICH1 KRTAP10-10 MDFI PPP1R14A SNCA
Entrez ID		353333	1456
HPRD ID		11185	05034
Ensembl ID		ENSG00000221859	ENSG00000151292
Uniprot IDs		P60014	A0A8V8TKT3 Q9Y6M4
PDB IDs			2CHL 2IZR 2IZS 2IZT 2IZU 4G16 4G17 4HGL 4HGS 6GRO
Enriched GO Terms of Interacting Partners?		Epidermis Development Keratinization Tissue Development Intermediate Filament Identical Protein Binding Keratin Filament	Protein Sequestering Activity Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Regulation Of Phosphorus Metabolic Process Transporter Regulator Activity Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake DNA Secondary Structure Binding Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process
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