KRTAP10-10 and LCE3C

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		KRTAP10-10	LCE3C
Description		keratin associated protein 10-10	late cornified envelope 3C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Epidermis Development Keratinization Killing Of Cells Of Another Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		Keratinization	Formation of the cornified envelope
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		26 interacting genes: AXIN2 CATSPER1 CREB5 CSNK1G3 CTSZ CYSRT1 HOXA1 KRTAP10-8 KRTAP4-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-3 LCE1B LCE1C LCE1E LCE1F LCE2C LCE3B LCE3C NBPF19 NDUFB7 NOTCH2NLA PLEKHF2 ZNF473 ZNF587	66 interacting genes: ADAMTSL4 ALPP CHIC2 CYP21A2 CYSRT1 EFEMP2 GRN HOXA1 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1F LCE2B LCE2D LCE4A LCE5A MDFI NBPF19 NOTCH2NLA NUFIP2 PCSK5 PLSCR1 RGS17 RGS20 SPRY1 SPRY2 TRIM42 TSPAN4 VASN ZNF655
Entrez ID		353333	353144
HPRD ID		11185	17262
Ensembl ID		ENSG00000221859	ENSG00000244057
Uniprot IDs		P60014	Q5T5A8
PDB IDs
Enriched GO Terms of Interacting Partners?		Epidermis Development Keratinization Tissue Development Intermediate Filament Identical Protein Binding Keratin Filament	Intermediate Filament Keratin Filament Epidermis Development Keratinization Hair Cycle Cytosol Tissue Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding Bud Elongation Involved In Lung Branching Regulation Of Lens Fiber Cell Differentiation Protein Binding Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Neurotrophin TRK Receptor Signaling Pathway
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