RNF38 and DTX3

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		RNF38	DTX3
Gene Name		ring finger protein 38	deltex 3, E3 ubiquitin ligase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Sperm Flagellum	Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity	Zinc Ion Binding Ligase Activity
	Biological Process	Male Gonad Development Protein Ubiquitination	Notch Signaling Pathway Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: DTX3 DZIP3 RNF114 TP53 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2H ZDHHC17	25 interactors: DTX1 DTX2 RNF141 RNF38 TRAF4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2W UEVLD USP1 USP2 USP21 XIAP ZDHHC17
Entrez ID		152006	196403
HPRD ID		11519	16842
Ensembl ID		ENSG00000137075	ENSG00000178498
Uniprot IDs		Q9H0F5	Q8N9I9
PDB IDs		1X4J
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein K11-linked Ubiquitination Cellular Response To Oxygen Levels Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Protein Modification Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Protein Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Response To Hypoxia Toll-like Receptor Signaling Pathway Protein Metabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Activation Of Innate Immune Response Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Innate Immune Response Proteolysis Involved In Cellular Protein Catabolic Process Response To Transforming Growth Factor Beta Cellular Protein Catabolic Process Protein Catabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Innate Immune Response Cellular Metabolic Process Cellular Macromolecule Catabolic Process BMP Signaling Pathway Response To Abiotic Stimulus Immune Response-regulating Signaling Pathway Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Negative Regulation Of Helicase Activity Immune Response Notch Signaling Pathway Cellular Response To Growth Factor Stimulus Negative Regulation Of Mitotic Cell Cycle Phase Transition Response To Growth Factor Mitotic Cell Cycle Checkpoint Positive Regulation Of Immune Response Protein K27-linked Ubiquitination	Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Protein K48-linked Ubiquitination Protein Polyubiquitination Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Protein Metabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Metabolic Process Proteolysis ISG15-protein Conjugation Protein K63-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Metabolic Process Regulation Of Proteolysis Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Cellular Response To Stress Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Protein Monoubiquitination Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To DNA Damage Stimulus
Tagcloud ?		bipartite bodies confirm demonstrate discrete e3 encodes finally finger foci hek293t isoform ligase localization localized nls nuclear nucleus overexpression p53 partner play pml regulating relocalization ring ubiquitin ubiquitinate unknown
Tagcloud (Difference) ?		bipartite bodies confirm demonstrate discrete e3 encodes finally finger foci hek293t isoform ligase localization localized nls nuclear nucleus overexpression p53 partner play pml regulating relocalization ring ubiquitin ubiquitinate unknown
Tagcloud (Intersection) ?