RNF38 and KRTAP21-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RNF38	KRTAP21-2
Description		ring finger protein 38	keratin associated protein 21-2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Sperm Flagellum	Cytosol Intermediate Filament
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Male Gonad Development Protein Ubiquitination
Pathways			Keratinization
Drugs
Diseases
GWAS		Bipolar disorder (inflammation and infection response interaction) ( 25781172)
Interacting Genes		29 interacting genes: CYSRT1 DTX3 DZIP3 KPNA4 KPRP KRTAP10-8 KRTAP11-1 KRTAP19-5 KRTAP21-2 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 NEDD4 OXER1 RBM11 RNF114 RNF208 RUNX1 TP53 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2H UBE2N YAP1 ZDHHC17	30 interacting genes: ADAMTSL4 ATXN1L BEX2 CLCNKA DMRTB1 EFEMP1 FAM221A FOXD2 GATA2 KRTAP10-1 KRTAP12-2 KRTAP26-1 LCE1A LCE2A LCE5A MKRN3 NTN4 PLSCR4 POU4F2 PRR13 RNF38 RNF44 SMARCC1 SMN1 SMN2 SNRPC SPAG8 TCF7L2 VENTX ZIC1
Entrez ID		152006	337978
HPRD ID		11519	11215
Ensembl ID		ENSG00000137075	ENSG00000187026
Uniprot IDs		Q9H0F5	Q3LI59
PDB IDs		1X4J 4V3K 4V3L 7OJX
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Ubiquitination Ubiquitin-protein Transferase Activity Protein Polyubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Intermediate Filament Ubiquitin Protein Ligase Activity Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Protein Modification Process Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cardiac Muscle Tissue Regeneration Proteolysis Protein K11-linked Ubiquitination Macromolecule Catabolic Process Transferase Activity Protein Monoubiquitination Protein Metabolic Process Protein Autoubiquitination Regulation Of Cellular Response To Growth Factor Stimulus Protein K63-linked Ubiquitination Catabolic Process Proline-rich Region Binding Positive Regulation Of Protein Polyubiquitination Protein Binding Protein K6-linked Ubiquitination	Developmental Process Sequence-specific DNA Binding SMN Complex Cajal Body Spliceosomal SnRNP Assembly Gemini Of Cajal Bodies Keratinization SMN-Sm Protein Complex DNA-templated Transcription Termination
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