CTRL and SERPINA3

Number of citations: 0 (PubMedID 8267879)
Data Source: HPRD (in vitro)

		CTRL	SERPINA3
Name		chymotrypsin like	serpin family A member 3
Structure		No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Region Extracellular Space Nucleus Extracellular Matrix Platelet Alpha Granule Lumen Secretory Granule Lumen Azurophil Granule Lumen Extracellular Exosome Blood Microparticle
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Proteolysis Protein Catabolic Process	Acute-phase Response Inflammatory Response Regulation Of Lipid Metabolic Process Maintenance Of Gastrointestinal Epithelium Response To Cytokine
Pathways		Developmental Lineage of Pancreatic Acinar Cells	Platelet degranulation Neutrophil degranulation
Drugs		None	Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
GWAS		Refractive error ( 32231278 ) Schizophrenia ( 25056061 29483656 )	Blood protein levels ( 30072576 ) Body mass index ( 23669352 ) Prostate-specific antigen levels ( 28139693 ) Serum total protein levels ( 29403010 )
Novel Interactors		2 novel interactors: DYNC1LI2 TUBG1	None recorded
Interacting Genes		4 interacting genes: CLDN5 FAM209A FATE1 SERPINA3	29 interacting genes: ABCC5 ADAMTS4 ADH1B APP CELA1 CFTR CMA1 CTRB1 CTRC CTRL CTSG DNAJC1 ELANE ERBB2 F5 HOXB1 HSP90AA1 KLK13 KLK2 KLK3 KLK4 LAMC3 LMNB1 MMP1 MST1 NFKB1 POLA1 POLR1H SGCD
Entrez ID		1506	12
HPRD ID		00344	00120
Ensembl ID		ENSG00000141086	ENSG00000196136
Uniprot IDs		P40313	P01011
PDB IDs		Not available	1AS4 1QMN 2ACH 3CAA 3DLW 4CAA 6HGE 9C2T 9D7K
GO Terms Enriched among Interactors		None	Serine-type Endopeptidase Activity Serine-type Peptidase Activity Peptidase Activity Extracellular Matrix Disassembly Secretory Granule Proteolysis Extracellular Region Endopeptidase Activity Hydrolase Activity Extracellular Matrix Organization Extracellular Structure Organization Extracellular Space Protein Metabolic Process Macromolecule Metabolic Process Extracellular Matrix Protein Maturation Protein Processing Amelogenesis Defense Response To Fungus ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Defense Response To Bacterium Response To Fungus Neutrophil-mediated Killing Of Bacterium Glial Cell Development Angiotensin Maturation Protein-containing Complex Localization Response To Yeast Platelet Alpha Granule Protein Catabolic Process Response To Bacterium Neutrophil Mediated Immunity Protein-folding Chaperone Binding Basolateral Plasma Membrane Amyloid-beta Complex Monoatomic Ion Homeostasis Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Monoatomic Cation Homeostasis Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Biofilm Matrix Disassembly Killing By Host Of Symbiont Cells Glycoprotein Catabolic Process Biosynthetic Process Of Antibacterial Peptides Active Against Gram-negative Bacteria Positive Regulation Of MAP Kinase Activity Regulation Of Protein Serine/threonine Kinase Activity Myelin Sheath