FAM220A

Description		family with sequence similarity 220 member A
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Cytoplasmic Vesicle
	Molecular Function	Protein Binding STAT Family Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		3 interacting genes: NEK6 PTPN2 TEKT4
Entrez ID		84792
HPRD ID		14427
Ensembl ID		ENSG00000178397
Uniprot IDs		Q7Z4H9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Positive Thymic T Cell Selection Negative Regulation Of Positive Thymic T Cell Selection Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Interleukin-2-mediated Signaling Pathway Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway Insulin Receptor Recycling Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Type II Interferon-mediated Signaling Pathway Negative Regulation Of Macrophage Differentiation Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of T Cell Differentiation In Thymus Protein Kinase Binding Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon STAT Family Protein Binding Mitotic Nuclear Membrane Disassembly Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Nuclear Membrane Disassembly Regulation Of PERK-mediated Unfolded Protein Response Membrane Disassembly Negative Regulation Of Peptidyl-tyrosine Phosphorylation Endosome Lumen Negative Regulation Of Lipid Storage Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of T Cell Differentiation In Thymus Regulation Of Macrophage Differentiation Positive Regulation Of Gluconeogenesis Axonemal A Tubule Inner Sheath Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Receptor Recycling Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT Organelle Assembly Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Axonemal Microtubule Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Microtubule-based Process
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