TFAP4

Description		transcription factor AP-4
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion Transcription Repressor Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Host-mediated Suppression Of Viral Transcription Host-mediated Activation Of Viral Transcription Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Cellular Response To Dexamethasone Stimulus Regulation Of Mitotic Cell Cycle Phase Transition
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Lung function (FEV1/FVC) ( 26635082) Platelet count ( 32888494) Prostate-specific antigen levels ( 28139693) Serum alkaline phosphatase levels ( 33547301) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		12 interacting genes: AJUBA EXOSC8 GOLGA2 INCA1 MCRS1 PDE9A PTPN3 SFMBT2 TEKT4 TRAF1 TRAF4 VMAC
Entrez ID		7023
HPRD ID		11795
Ensembl ID		ENSG00000090447
Uniprot IDs		Q01664
PDB IDs
Enriched GO Terms of Interacting Partners?		Thioesterase Binding Cytoskeleton Tumor Necrosis Factor Receptor Binding
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