WFDC5 and STAG1

Number of citations of the paper that reports this interaction (PMID 17113138)
98

Data Source:
BioGRID (affinity chromatography technology, pull down)

		WFDC5	STAG1
Gene Name		WAP four-disulfide core domain 5	stromal antigen 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity	Chromatin Binding Protein Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Division
Pathways			Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: STAG1	6 interactors: CALM1 RAD21 SMAD2 SMAD9 STAG2 WFDC5
Entrez ID		149708	10274
HPRD ID		05518	05076
Ensembl ID		ENSG00000175121	ENSG00000118007
Uniprot IDs		Q8TCV5	Q6P275 Q8WVM7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of SMAD Protein Complex Assembly Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Androgen Receptor Signaling Pathway Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Protein Complex Assembly Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Intracellular Receptor Signaling Pathway Chromosome Segregation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mitotic Nuclear Division Negative Regulation Of Protein Phosphorylation Regulation Of Protein Complex Assembly	Midbrain Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Transforming Growth Factor Beta Receptor Signaling Pathway Stem Cell Maintenance Kidney Epithelium Development Zygotic Specification Of Dorsal/ventral Axis Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Negative Regulation Of Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Response To Organic Cyclic Compound Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Metabolic Process Meiotic Cell Cycle Negative Regulation Of DNA Endoreduplication Regulation Of High Voltage-gated Calcium Channel Activity Chromosome Segregation Positive Regulation Of Mesoderm Development Primary MiRNA Processing Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Stem Cell Development Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Activin Receptor Signaling Pathway Mullerian Duct Regression Regulation Of Nitrogen Compound Metabolic Process Kidney Development Stem Cell Differentiation Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of DNA Endoreduplication Mitotic Nuclear Division Renal System Development Detection Of Calcium Ion Protein Localization To Chromatin SMAD Protein Complex Assembly Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Paraxial Mesoderm Morphogenesis Urogenital System Development Nodal Signaling Pathway Positive Regulation Of Peptidyl-threonine Phosphorylation
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