STAG1 and STAG2

Number of citations of the paper that reports this interaction (PMID 11076961)
108

Data Source:
HPRD (in vitro, in vivo)

		STAG1	STAG2
Gene Name		stromal antigen 1	stromal antigen 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Plasma Membrane Actin Cytoskeleton Membrane Intermediate Filament Cytoskeleton
	Molecular Function	Chromatin Binding Protein Binding	Chromatin Binding Protein Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Division	Mitotic Cell Cycle Sister Chromatid Cohesion Mitotic Nuclear Division Stem Cell Maintenance Negative Regulation Of DNA Endoreduplication Cell Division Meiotic Cell Cycle
Pathways		Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase	Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CALM1 RAD21 SMAD2 SMAD9 STAG2 WFDC5	4 interactors: PLK1 RAD21 SSU72 STAG1
Entrez ID		10274	10735
HPRD ID		05076	05077
Ensembl ID		ENSG00000118007	ENSG00000101972
Uniprot IDs		Q6P275 Q8WVM7	Q6AI02 Q6MZM3 Q6MZP3 Q8N3U4
PDB IDs
Enriched GO Terms of Interacting Partners?		Midbrain Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Transforming Growth Factor Beta Receptor Signaling Pathway Stem Cell Maintenance Kidney Epithelium Development Zygotic Specification Of Dorsal/ventral Axis Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Negative Regulation Of Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Response To Organic Cyclic Compound Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Metabolic Process Meiotic Cell Cycle Negative Regulation Of DNA Endoreduplication Regulation Of High Voltage-gated Calcium Channel Activity Chromosome Segregation Positive Regulation Of Mesoderm Development Primary MiRNA Processing Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Stem Cell Development Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Activin Receptor Signaling Pathway Mullerian Duct Regression Regulation Of Nitrogen Compound Metabolic Process Kidney Development Stem Cell Differentiation Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of DNA Endoreduplication Mitotic Nuclear Division Renal System Development Detection Of Calcium Ion Protein Localization To Chromatin SMAD Protein Complex Assembly Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Paraxial Mesoderm Morphogenesis Urogenital System Development Nodal Signaling Pathway Positive Regulation Of Peptidyl-threonine Phosphorylation	Protein Localization To Chromatin Chromosome Segregation Protein Localization To Chromosome Mitotic Nuclear Division Cell Division Mitotic Cell Cycle Process Mitotic Cell Cycle Meiotic Nuclear Division Activation Of APC-Cdc20 Complex Activity Cell Cycle Process Meiotic Cell Cycle Dephosphorylation Of RNA Polymerase II C-terminal Domain Polar Body Extrusion After Meiotic Divisions Cell Cycle Negative Regulation Of SMAD Protein Complex Assembly Negative Regulation Of Protein Phosphorylation Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Positive Regulation Of Mitotic Metaphase/anaphase Transition Metaphase/anaphase Transition Of Mitotic Cell Cycle Negative Regulation Of Phosphorylation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Chromosome Segregation Positive Regulation Of Peptidyl-threonine Phosphorylation Protein Localization To Organelle Protein Destabilization Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity MRNA Polyadenylation G2 DNA Damage Checkpoint Mitotic Spindle Assembly Checkpoint Mitotic Nuclear Envelope Disassembly Female Meiotic Division Spindle Assembly Checkpoint RNA Polyadenylation Mitotic Spindle Checkpoint Negative Regulation Of Cellular Protein Metabolic Process Androgen Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Nuclear Envelope Disassembly Cellular Response To DNA Damage Stimulus Reciprocal Meiotic Recombination Mitotic Cytokinesis Microtubule Bundle Formation Negative Regulation Of Protein Metabolic Process Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Organelle Organization
Tagcloud ?			aml antecedent asxl1 bcor clinicopathologic clonal de define highlights identifiable leukemogenesis leukemogenic malignancy mutational myeloid novo persist prodrome remissions rigorously serial sf3b1 shares srsf2 subset u2af1 unselected worse zrsr2
Tagcloud (Difference) ?			aml antecedent asxl1 bcor clinicopathologic clonal de define highlights identifiable leukemogenesis leukemogenic malignancy mutational myeloid novo persist prodrome remissions rigorously serial sf3b1 shares srsf2 subset u2af1 unselected worse zrsr2
Tagcloud (Intersection) ?