ZNF35 and EEF2KMT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF35	EEF2KMT
Description		zinc finger protein 35	eukaryotic elongation factor 2 lysine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Methyltransferase Activity Protein-lysine N-methyltransferase Activity Transferase Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Spermatogenesis Cellular Response To Retinoic Acid	Peptidyl-lysine Trimethylation Methylation
Pathways			Protein methylation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)
Interacting Genes		32 interacting genes: APP ATPAF2 CCDC136 CDC5L CDR2 CDR2L CEP70 CREB1 CWF19L2 EEF2KMT EXOC8 FSD2 GEMIN4 GOLGA2 GOLGA6L9 GRIPAP1 HOMER3 HOMEZ HOOK1 HOOK2 LZTS1 MCC MTUS2 MYD88 NDEL1 PIBF1 PICK1 PNMA1 PRKAR1B TRAF2 YJU2B ZBTB8A	12 interacting genes: HPRT1 IFT88 KIAA1328 LNX1 NR0B1 PICK1 PRKAR1B PRTFDC1 TRIP13 ZNF213 ZNF35 ZNF620
Entrez ID		7584	196483
HPRD ID		01920	18018
Ensembl ID		ENSG00000169981	ENSG00000118894
Uniprot IDs		P13682	K7ES84 Q96G04
PDB IDs			8FZB
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Positive Regulation Of Long-term Synaptic Potentiation Cytoskeleton-dependent Intracellular Transport Regulation Of Synaptic Plasticity FHF Complex Regulation Of Long-term Synaptic Potentiation Microtubule Binding Protein Localization To Perinuclear Region Of Cytoplasm Post-mRNA Release Spliceosomal Complex Centrosome Modulation Of Chemical Synaptic Transmission Vesicle Organization HOPS Complex Microtubule Protein Binding Endosome Organization Microtubule-based Process	Guanine Salvage Hypoxanthine Phosphoribosyltransferase Activity GMP Catabolic Process Guanine Metabolic Process Purine Ribonucleoside Salvage Purine Nucleobase Biosynthetic Process Nucleoside Salvage Purine Nucleoside Monophosphate Catabolic Process Purine Nucleobase Metabolic Process Purine Nucleoside Metabolic Process GMP Metabolic Process Purine-containing Compound Salvage Nucleoside Metabolic Process Hippocampal Mossy Fiber To CA3 Synapse Ciliary Base DNA Hairpin Binding Guanine Phosphoribosyltransferase Activity Nucleoside Monophosphate Metabolic Process Purine Ribonucleotide Catabolic Process Hypoxanthine Salvage Purine Nucleotide Catabolic Process Adenine Metabolic Process Hypoxanthine Biosynthetic Process Meiotic Recombination Checkpoint Signaling Nucleotide Catabolic Process AF-2 Domain Binding Hypoxanthine Metabolic Process Response To Silicon Dioxide Membrane Curvature Sensor Activity GMP Salvage Nucleoside Phosphate Catabolic Process IMP Salvage Centriolar Satellite Male Gamete Generation Spermatogenesis Positive Regulation Of Dopamine Metabolic Process AMP Salvage Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation CAMP-dependent Protein Kinase Regulator Activity Female Meiosis I Gamete Generation Metal Ion Binding Positive Regulation Of Fear Response Meiotic Cell Cycle Checkpoint Signaling Negative Regulation Of Actin Nucleation
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