B3GALNT2 and TMBIM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		B3GALNT2	TMBIM1
Description		beta-1,3-N-acetylgalactosaminyltransferase 2	transmembrane BAX inhibitor motif containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane	Golgi Membrane Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Protein Binding UDP-glycosyltransferase Activity Acetylgalactosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Hexosyltransferase Activity	Death Receptor Binding Calcium Channel Activity Protein Binding
	Biological Process	Protein Glycosylation Protein O-linked Glycosylation	Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Calcium Ion Transmembrane Transport Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Fas Signaling Pathway Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Blood Vessel Remodeling
Pathways		DAG1 core M3 glycosylations	Neutrophil degranulation
Drugs
Diseases
GWAS		Body mass index ( 28892062)	Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Gallstone disease ( 30504769) Glycated hemoglobin levels ( 34059833) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 23128233 28067908) Red cell distribution width ( 27863252) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		1 interacting genes: TMBIM1	13 interacting genes: B3GALNT2 BIK CD33 F2RL1 GGT6 PROK2 RCHY1 RIC3 SLC10A1 SOCS5 TMEM242 TRIM55 TRIM63
Entrez ID		148789	64114
HPRD ID		16533	17884
Ensembl ID		ENSG00000162885	ENSG00000135926
Uniprot IDs		Q8NCR0	B3KSM0 B4DUD2 Q969X1
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Fas Signaling Pathway Positive Regulation Of Blood Vessel Remodeling Negative Regulation Of Fas Signaling Pathway Regulation Of Blood Vessel Remodeling Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Death Receptor Binding Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Tissue Remodeling Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Calcium Channel Activity Regulation Of Tissue Remodeling Specific Granule Membrane Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Cell Periphery Negative Regulation Of Catalytic Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Localization To Membrane Negative Regulation Of Neuron Apoptotic Process Calcium Ion Transmembrane Transport Negative Regulation Of Protein Localization Negative Regulation Of Apoptotic Signaling Pathway Calcium Ion Transport Regulation Of Neuron Apoptotic Process
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