TMBIM1

Gene Name		transmembrane BAX inhibitor motif containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Golgi Apparatus Endosome Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Death Receptor Binding
	Biological Process	Negative Regulation Of Metalloenzyme Activity Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Fas Signaling Pathway Positive Regulation Of Blood Vessel Remodeling
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		2 interactors: RCHY1 SOCS5
Entrez ID		64114
HPRD ID		17884
Ensembl ID		ENSG00000135926
Uniprot IDs		B3KSM0 Q969X1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Protein Catabolic Process Negative Regulation Of T-helper 2 Cell Differentiation Positive Regulation Of T-helper 1 Cell Differentiation Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Proteolysis Regulation Of T-helper 1 Cell Differentiation Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of T-helper Cell Differentiation Positive Regulation Of T-helper 1 Type Immune Response Negative Regulation Of Alpha-beta T Cell Differentiation Negative Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Type 2 Immune Response Negative Regulation Of JAK-STAT Cascade Negative Regulation Of Alpha-beta T Cell Activation Negative Regulation Of Receptor Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of T-helper Cell Differentiation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Protein Metabolic Process Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of T-helper Cell Differentiation Negative Regulation Of T Cell Differentiation Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Protein Autoubiquitination Positive Regulation Of Alpha-beta T Cell Differentiation Regulation Of Type 2 Immune Response Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Lymphocyte Differentiation JAK-STAT Cascade Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Tyrosine Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of T Cell Differentiation Regulation Of JAK-STAT Cascade Positive Regulation Of Lymphocyte Differentiation Negative Regulation Of T Cell Activation
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