ANKRD29 and CRACR2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ANKRD29	CRACR2A
Description		ankyrin repeat domain 29	calcium release activated channel regulator 2A
Image		No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Immunological Synapse Extracellular Region Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Vesicle Trans-Golgi Network Membrane Weibel-Palade Body Specific Granule Lumen Specific Granule
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity G Protein Activity Calcium Ion Binding Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process		Store-operated Calcium Entry Adaptive Immune Response Immune System Process Monoatomic Ion Transport Calcium Ion Transport Intracellular Protein Localization Vesicle-mediated Transport Endosomal Transport Activation Of Store-operated Calcium Channel Activity Response To Histamine T-helper 1 Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Calcium Ion Transport
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24256812)	Femur bone mineral density x serum urate levels interaction ( 34046847) Severe insulin-deficient type 2 diabetes ( 34737425)
Interacting Genes		10 interacting genes: CABP2 CRACR2A FAM90A1 FERMT3 GTF2H5 GYPA HLCS MRPL53 RABGEF1 USP32	35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655
Entrez ID		147463	84766
HPRD ID		12464	10079
Ensembl ID		ENSG00000154065	ENSG00000130038
Uniprot IDs		Q8N6D5	Q9BSW2
PDB IDs			6PSD
Enriched GO Terms of Interacting Partners?			Identical Protein Binding
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