IQCE and GPSM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IQCE	GPSM3
Description		IQ motif containing E	G protein signaling modulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cilium Membrane Cell Projection Ciliary Membrane	Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding GTPase Regulator Activity
	Biological Process	Limb Morphogenesis	Positive Regulation Of Leukocyte Chemotaxis Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		Activation of SMO	G alpha (i) signalling events
Drugs
Diseases
GWAS		Anxiety disorders ( 31906708) Food allergy (parent-of-origin effect) ( 29489655) Urate levels in lean individuals ( 25811787)	A body shape index ( 34021172) Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		18 interacting genes: CALM1 CALM2 CALM3 CARD9 CEP70 CRK GOLGA2 GPSM3 HNRNPF HOOK2 LZTS2 MGAT5B MTUS2 PSMA3 RPGRIP1 SPAG5 TRIM23 TRIM27	44 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KCNJ5-AS1 KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPMIP5 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 ZNF20 ZNF581
Entrez ID		23288	63940
HPRD ID		11050	13605
Ensembl ID		ENSG00000106012	ENSG00000213654
Uniprot IDs		A0A087WX19 A0A087WX45 B3KRY4 B4DDX4 B4DXN1 Q6IPM2	A0A024RCP6 Q9Y4H4
PDB IDs
Enriched GO Terms of Interacting Partners?		Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Centrosome Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Detection Of Calcium Ion Spindle Pole Cytoskeleton Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calyx Of Held Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Calcium Channel Complex Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Establishment Of Localization In Cell Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Sperm Midpiece Positive Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Microtubule Long-term Synaptic Potentiation Sarcomere Cell Cycle G2/M Phase Transition Negative Regulation Of Voltage-gated Calcium Channel Activity Vesicle Cytoplasm Neural Nucleus Development Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Negative Regulation Of Monoatomic Ion Transmembrane Transport Adenylate Cyclase Binding Voltage-gated Potassium Channel Complex Calcium-dependent Protein Binding	Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex
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