BICDL2 and KLC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BICDL2	KLC3
Description		BICD family like cargo adaptor 2	kinesin light chain 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Mitochondrion Cytoskeleton Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding Microtubule Binding Kinesin Binding
	Biological Process	Vesicle Transport Along Microtubule Golgi To Secretory Granule Transport	Microtubule-based Movement Spermatogenesis Spermatid Development Axo-dendritic Transport Cell Differentiation Sperm Mitochondrial Sheath Assembly
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS			Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		7 interacting genes: API5 CDK17 CFTR KLC3 PKP1 RPL9 TSGA10IP	41 interacting genes: ABI3 ATP23 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC CT55 DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KLHL21 KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PCBD2 PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 USHBP1 VPS52 WAC WASHC1 YWHAG YWHAH YWHAQ ZNF417 ZNF572
Entrez ID		146439	147700
HPRD ID		11237	03212
Ensembl ID		ENSG00000162069	ENSG00000104892
Uniprot IDs		A1A5D9	Q6P597
PDB IDs
Enriched GO Terms of Interacting Partners?		Transepithelial Water Transport Epithelial Fluid Transport Water Transport Fluid Transport Transepithelial Transport Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Anion Channel Activity Desmosome Maintenance Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Cap-dependent Translational Initiation Positive Regulation Of Enamel Mineralization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Intermediate Filament Binding Positive Regulation Of Cytoplasmic Translational Initiation Nuclear Stress Granule Ameloblast Differentiation Intermediate Filament Bundle Assembly Desmosome Assembly Negative Regulation Of Fibroblast Apoptotic Process Sperm Mitochondrial Sheath Assembly Amelogenesis Ciliary Rootlet ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Fibroblast Apoptotic Process	Ciliary Rootlet Organelle Localization Establishment Of Organelle Localization Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Anterograde Dendritic Transport Protein Transport Along Microtubule Anterograde Axonal Transport Establishment Of Vesicle Localization Identical Protein Binding Dendritic Transport Vesicle Localization Plus-end-directed Microtubule Motor Activity Axon Cytoplasm Retrograde Axonal Transport Axonal Transport Dendrite Cytoplasm Axo-dendritic Transport Postsynaptic Cytosol Protein Binding Retrograde Neuronal Dense Core Vesicle Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Cytoskeleton-dependent Intracellular Transport Cytoskeleton Vesicle Transport Along Microtubule Kinesin Complex Microtubule-based Transport Establishment Of Localization In Cell Dense Core Granule Cytoskeletal Transport Receptor Localization To Synapse Presynapse Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cytosolic Transport Vesicle Fusion To Plasma Membrane Vesicle Cytoskeletal Trafficking Microtubule Binding Microtubule Motor Activity Intracellular Transport Protein Localization To Synapse Microtubule-based Process Synaptic Vesicle Membrane Organization Intracellular Protein Localization Insulin-like Growth Factor Receptor Binding Establishment Of Protein Localization Intermediate Filament Organization Secretory Granule Localization Protein Localization To Cell Junction Intermediate Filament Cytoskeleton Organization
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