FAM109A and PLEKHJ1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		FAM109A	PLEKHJ1
Gene Name		family with sequence similarity 109, member A	pleckstrin homology domain containing, family J member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Trans-Golgi Network Clathrin-coated Vesicle Recycling Endosome
	Molecular Function	Protein Binding Protein Homodimerization Activity
	Biological Process	Receptor Recycling Endosome Organization Retrograde Transport, Endosome To Golgi
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: PLEKHJ1	7 interactors: ACVR1 APP DNMT3B FAM109A IKBKG PPBP TGFBR1
Entrez ID		144717	55111
HPRD ID		08127	15150
Ensembl ID		ENSG00000198324	ENSG00000104886
Uniprot IDs		Q8N4B1	K7EN12 Q9NW61
PDB IDs		3QIS
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Cellular Protein Metabolic Process Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Pharyngeal System Development Positive Regulation Of Gene Expression Activin Receptor Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Signal Transduction By Phosphorylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Peptidyl-threonine Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Platelet Degranulation Inflammatory Response Locomotion Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Transcription, DNA-templated Endocardial Cushion Cell Fate Commitment Defense Response Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Mesenchymal Cell Development Positive Regulation Of Macromolecule Biosynthetic Process Wound Healing Regulation Of Cell Differentiation Synaptic Growth At Neuromuscular Junction Positive Regulation Of Cellular Biosynthetic Process Regulation Of Signaling Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Mesenchymal Cell Differentiation Cell Surface Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Cell Activation Regulation Of Protein Binding Response To Wounding Collateral Sprouting In Absence Of Injury S-adenosylmethioninamine Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Response To Stress Phosphorylation Cellular Response To Organic Substance
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