PHETA1 and KRTAP13-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PHETA1	KRTAP13-2
Description		PH domain containing endocytic trafficking adaptor 1	keratin associated protein 13-2
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Clathrin-coated Vesicle Cytoplasmic Vesicle Recycling Endosome	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Protein Homodimerization Activity	Structural Molecule Activity Protein Binding
	Biological Process	Receptor Recycling Endosome Organization Retrograde Transport, Endosome To Golgi
Pathways			Keratinization
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: ABI2 C11orf68 CYSRT1 FCHO1 GRB2 HOXA1 KRTAP1-3 KRTAP13-2 KRTAP6-3 NCK2 OIP5 PLEKHJ1 SNCA SORBS3	81 interacting genes: ANAPC11 ANXA11 BCL6 C22orf39 CBFA2T2 CCDC125 CCDC24 CCDC57 CCNK CFAP68 CRYBA1 CSKMT CYSRT1 ENKD1 EPDR1 ETFDH FANCL FBXO17 FCHO1 GATA3 GEMIN4 GNE GPS2 GRN HNRNPH1 HOXA1 HR KCTD9 KLHL38 KPRP KRT3 KRTAP1-1 KRTAP10-5 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP4-4 KRTAP4-5 KRTAP9-2 MAGOHB MEOX2 MGAT5B NBPF19 NEK8 NHLRC4 NOTCH2NLA OIP5 OTX1 P4HB PATZ1 PHETA1 PITX1 POU2AF1 RECK RHOXF2 SAXO4 SLC25A18 SLIT1 SMUG1 SNRPC SPEF1 SPMIP9 SSC4D STK16 TCAF1 TLE5 TNS2 TRAPPC6A TRIM68 TSPYL6 TSSK3 UNC5CL VGLL3 VWC2 YPEL3 ZIC1
Entrez ID		144717	337959
HPRD ID		08127	11201
Ensembl ID		ENSG00000198324	ENSG00000182816
Uniprot IDs		Q8N4B1	Q52LG2
PDB IDs		3QIS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cytoskeleton Organization Regulation Of Actin Filament Organization Positive Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Cytoskeletal Anchor Activity Regulation Of Actin Filament-based Process Intermediate Filament Receptor-mediated Endocytosis Vesicle Membrane Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Adaptor Activity Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Actin Filament Polymerization Semicircular Canal Formation Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Cellular Component Organization Receptor Internalization Positive Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Grb2-EGFR Complex Regulation Of Cell Activation Epidermal Growth Factor Receptor Signaling Pathway Abducens Nerve Formation Optokinetic Behavior Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Zonula Adherens Assembly Identical Protein Binding ERBB Signaling Pathway Regulation Of Organelle Organization Signaling Adaptor Activity Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Protein Polymerization Cytosol Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Pericentric Heterochromatin Organization CENP-A Recruiting Complex	Intermediate Filament Keratin Filament Protein Binding
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