CRYBA2 and UNKL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CRYBA2	UNKL
Description		crystallin beta A2	unk like zinc finger
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Cytosol
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding
	Biological Process	Lens Development In Camera-type Eye Visual Perception	Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Height ( 18391951 31562340) Macular thickness ( 30535121) Neutrophil percentage of white cells ( 32888494) Systolic blood pressure ( 28234671) Type 2 diabetes (adjusted for BMI) ( 30297969)	Refractive error ( 32231278) Serum immune biomarker levels ( 32066700)
Interacting Genes		27 interacting genes: ANAPC11 ARID5A BPIFA1 C10orf55 C22orf39 CALCOCO1 CCDC33 CRYBB1 CRYBB2 CRYBB3 CTDSP1 CYSRT1 FHL3 FHL5 KRTAP11-1 KRTAP13-3 KRTAP7-1 LASP1 NFKBID OXER1 PRR22 RUSC1 TRAF2 TRIP13 UNKL VAC14 YPEL3	42 interacting genes: APOBEC3C ATXN1L BAG3 BAG4 CABP2 CARD9 CPSF2 CPSF7 CREB5 CRYBA2 CTBP1 DDX50 DMRTB1 EXOSC7 EXOSC8 FBLN1 FRS3 HNRNPF HOOK1 HOXA1 KCTD9 KDM1A KRT31 LMO1 MGAT5B NID2 NTAQ1 POLR1C PPP1R16A QKI RAB26 RAC1 RBPMS RNF10 RPS28 SAXO4 SMARCD2 SRPK2 TFIP11 TGM7 TRIM55 TRIM63
Entrez ID		1412	64718
HPRD ID		02905	15612
Ensembl ID		ENSG00000163499	ENSG00000059145
Uniprot IDs		P53672	A0A0A0MRZ1 E9PDK2 Q9H9P5
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Eye Lens Lens Development In Camera-type Eye	RNA Binding U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing RNA Processing Transcription Coactivator Activity Nucleus RNA Metabolic Process MRNA Metabolic Process Negative Regulation Of Protein Targeting To Mitochondrion RNA 3'-end Processing Exoribonuclease Complex Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process Negative Regulation Of Establishment Of Protein Localization To Mitochondrion U4 SnRNA 3'-end Processing Identical Protein Binding RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) TRNA Decay Nuclear MRNA Surveillance Ruffle Assembly Protein Binding Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Adenyl-nucleotide Exchange Factor Activity MRNA Processing RRNA Catabolic Process Nuclear Exosome (RNase Complex) Exosome (RNase Complex) MRNA Cleavage And Polyadenylation Specificity Factor Complex Macromolecule Metabolic Process Positive Regulation Of Myelination Regulation Of RNA Splicing
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