EPDR1 and KRTAP4-11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EPDR1	KRTAP4-11
Description		ependymin related 1	keratin associated protein 4-11
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosome Lysosomal Lumen	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Calcium Ion Binding Protein Binding Phospholipid Binding Lipid Binding Identical Protein Binding Ganglioside GM1 Binding	Protein Binding
	Biological Process	Cell-matrix Adhesion Myofibroblast Contraction	Hair Cycle
Pathways			Keratinization
Drugs
Diseases
GWAS		Dupuytren's disease ( 21732829 28886342) Glaucoma (primary angle closure) ( 27064256) Heel bone mineral density ( 28869591 30598549) Height ( 31562340) Lateral ventricle volume ( 31530798) Lumbar spine bone mineral density ( 29499414) Rosacea symptom severity ( 29771307)
Interacting Genes		13 interacting genes: ADAMTSL4 EHMT2 HOXA1 IGFBP6 KRT31 KRT34 KRTAP10-8 KRTAP13-2 KRTAP4-11 PM20D2 TNS2 TRIP6 UBQLN4	90 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CREB5 CYSRT1 DHRS1 EHHADH ENKD1 EPDR1 FAM221A FAM76B FBXO34 GATA1 GLRX3 GNE GRAP2 HOXA1 KLHL38 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP15-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-3 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NECTIN3 NOTCH2NLA NR4A3 NUFIP2 OTX1 P4HB PLSCR1 POTEB3 POU4F2 PRPF31 RGS17 SHFL SLC23A1 SMCP SPRY2 TGFB1 TSPAN4 VASN VGLL3 ZNF417 ZNF552 ZNF837
Entrez ID		54749	653240
HPRD ID		16865
Ensembl ID		ENSG00000086289	ENSG00000212721
Uniprot IDs		Q96J80 Q9UM22	Q9BYQ6
PDB IDs		6E7O 6E8N 6JLD
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Identical Protein Binding Structural Molecule Activity Negative Regulation Of Macroautophagy Semicircular Canal Formation Insulin-like Growth Factor Binary Complex Histone H3K56 Methyltransferase Activity Pigment Cell Development Para-aminobenzoyl-glutamate Hydrolase Activity Structural Constituent Of Skin Epidermis Abducens Nerve Formation Optokinetic Behavior Intermediate Filament Organization Nuclear Proteasome Complex Folic Acid Catabolic Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Phenotypic Switching Negative Regulation Of Autophagosome Maturation Kinase Binding Negative Regulation Of Autophagy	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Identical Protein Binding Protein Binding
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