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COX8A and AMBP
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
COX8A
AMBP
Description
cytochrome c oxidase subunit 8A
alpha-1-microglobulin/bikunin precursor
Image
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Membrane
Mitochondrial Membrane
Respiratory Chain Complex IV
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Mitochondrial Inner Membrane
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Cell Surface
Membrane
Extracellular Matrix
Nuclear Membrane
Extracellular Exosome
Blood Microparticle
Matrix Side Of Mitochondrial Inner Membrane
Molecular Function
Cytochrome-c Oxidase Activity
Protein Binding
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Antioxidant Activity
Oxidoreductase Activity
Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor
Calcium Channel Inhibitor Activity
IgA Binding
Heme Binding
Carbohydrate Binding
Peptidase Inhibitor Activity
Chondroitin Sulfate Binding
Protein Homodimerization Activity
Calcium Oxalate Binding
Collagen Fibril Binding
Biological Process
Generation Of Precursor Metabolites And Energy
Oxidative Phosphorylation
Mitochondrial Electron Transport, Cytochrome C To Oxygen
Cellular Respiration
Proton Transmembrane Transport
Cell Adhesion
Female Pregnancy
Hemoglobin Metabolic Process
Protein Catabolic Process
Cellular Response To Reactive Oxygen Species
Heme Catabolic Process
Negative Regulation Of JNK Cascade
Negative Regulation Of Immune Response
Cellular Oxidant Detoxification
Cytochrome C Metabolic Process
Pathways
TP53 Regulates Metabolic Genes
Respiratory electron transport
Cytoprotection by HMOX1
Complex IV assembly
Scavenging of heme from plasma
Drugs
Cholic Acid
N-Formylmethionine
Diseases
GWAS
Bipolar disorder (
31043756
)
Interacting Genes
5 interacting genes:
AMBP
BATF
EDDM3B
MAGEA4
NPM1
12 interacting genes:
A2M
ALB
COX8A
DAAM1
ENO1
F2
FHL3
FN1
GRB2
PIK3CA
PIK3R3
STAT3
Entrez ID
1351
259
HPRD ID
00468
01467
Ensembl ID
ENSG00000176340
ENSG00000106927
Uniprot IDs
P10176
Q53XN1
P02760
PDB IDs
5Z62
8D4T
1BIK
3QKG
4ES7
4U30
6EJ7
6EJ8
6EJ9
6EJA
6EJB
6EJC
6EJD
Enriched GO Terms of Interacting Partners
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Myeloid Leukocyte Differentiation
Myeloid Cell Differentiation
T Cell Differentiation Involved In Immune Response
Mononuclear Cell Differentiation
Cytochrome C Metabolic Process
T Cell Activation Involved In Immune Response
Leukocyte Differentiation
IgE Receptor Activity
Regulation Of MRNA Stability Involved In Cellular Response To UV
Regulation Of EIF2 Alpha Phosphorylation By DsRNA
Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor
Collagen Fibril Binding
Calcium Oxalate Binding
Cytochrome Metabolic Process
Protein Homodimerization Activity
IgA Binding
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Type I Hypersensitivity
Mast Cell Apoptotic Process
Serotonin Secretion
Negative Regulation Of Mast Cell Apoptotic Process
Positive Regulation Of Type IIa Hypersensitivity
Cell Activation Involved In Immune Response
Serotonin Secretion By Platelet
T Cell Differentiation
Lymphocyte Activation Involved In Immune Response
Fc-gamma Receptor III Complex
Myeloid Leukocyte Activation
Fc-epsilon Receptor I Complex
Positive Regulation Of Type III Hypersensitivity
Regulation Of Endoribonuclease Activity
T-helper 17 Cell Differentiation
Positive Regulation Of Mast Cell Cytokine Production
IgE Binding
Regulation Of Mast Cell Apoptotic Process
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
Regulation Of Ribonuclease Activity
Positive Regulation Of Centrosome Duplication
Matrix Side Of Mitochondrial Inner Membrane
Positive Regulation Of Hypersensitivity
Interleukin-3-mediated Signaling Pathway
Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Negative Regulation Of Apoptotic Process
Regulation Of Adaptive Immune Response
Regulation Of Endodeoxyribonuclease Activity
Positive Regulation Of Protein Localization To Nucleolus
Ribosomal Small Subunit Export From Nucleus
Ribosomal Large Subunit Export From Nucleus
Granular Component
Negative Regulation Of Programmed Cell Death
Blood Microparticle
Regulation Of Growth
Acute-phase Response
Platelet Alpha Granule Lumen
Acute Inflammatory Response
Phosphatidylinositol 3-kinase Complex
Phosphatidylinositol 3-kinase Complex, Class IA
Insulin Receptor Signaling Pathway
1-phosphatidylinositol-3-kinase Activity
Positive Regulation Of ATP Biosynthetic Process
Endothelial Cell Migration
Insulin Receptor Substrate Binding
Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of ATP Biosynthetic Process
Negative Regulation Of Anoikis
Actin Cytoskeleton Organization
Phosphatidylinositol-3-phosphate Biosynthetic Process
Regulation Of Cellular Response To Hypoxia
Regulation Of Reactive Oxygen Species Metabolic Process
Signaling Receptor Binding
Regulation Of Cell Growth
Regulation Of Anoikis
Actin Filament-based Process
Positive Regulation Of Cell Growth
Cell Surface Receptor Signaling Pathway
Insulin-like Growth Factor Receptor Signaling Pathway
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of ATP Metabolic Process
Biological Process Involved In Interaction With Symbiont
Endodermal Cell Differentiation
Response To Wounding
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Phosphotyrosine Residue Binding
Phosphatidylinositol Phosphate Biosynthetic Process
Guanyl-nucleotide Exchange Factor Adaptor Activity
Positive Regulation Of Growth
Regulation Of Cellular Component Organization
Negative Regulation Of Gene Expression
Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Defense Response
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Cell Activation
Platelet Activation
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of Multicellular Organism Growth
Negative Regulation Of Complement Activation, Lectin Pathway
Enterobactin Binding
Exogenous Protein Binding
Endoplasmic Reticulum Lumen
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