COX8A and AMBP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		COX8A	AMBP
Gene Name		cytochrome c oxidase subunit VIIIA (ubiquitous)	alpha-1-microglobulin/bikunin precursor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Cytochrome-c Oxidase Activity	Serine-type Endopeptidase Inhibitor Activity Protein Binding Calcium Channel Inhibitor Activity IgA Binding Heme Binding Small Molecule Binding Protein Homodimerization Activity Calcium Oxalate Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process Transmembrane Transport Hydrogen Ion Transmembrane Transport	Receptor-mediated Endocytosis Cell Adhesion Female Pregnancy Negative Regulation Of Endopeptidase Activity Viral Process Protein-chromophore Linkage Protein Catabolic Process Heme Catabolic Process Negative Regulation Of JNK Cascade Negative Regulation Of Immune Response
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport Orphan transporters	Scavenging of heme from plasma
Drugs			Human Serum Albumin Serum albumin iodonated
Diseases
GWAS
Protein-Protein Interactions		2 interactors: AMBP NPM1	12 interactors: A2M ALB COX8A DAAM1 ENO1 F2 FHL3 FN1 GRB2 PIK3CA PIK3R3 STAT3
Entrez ID		1351	259
HPRD ID		00468	01467
Ensembl ID		ENSG00000176340	ENSG00000106927
Uniprot IDs		P10176 Q53XN1	P02760
PDB IDs			1BIK 3QKG 4ES7
Enriched GO Terms of Interacting Partners?		Regulation Of Endoribonuclease Activity Regulation Of EIF2 Alpha Phosphorylation By DsRNA Regulation Of Ribonuclease Activity Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Phosphorylation Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Viral Process Heme Catabolic Process Regulation Of Centriole Replication Negative Regulation Of Catalytic Activity Protein-chromophore Linkage Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Centrosome Duplication Negative Regulation Of Protein Metabolic Process CENP-A Containing Nucleosome Assembly Ribosome Assembly Negative Regulation Of JNK Cascade Histone Exchange DNA Replication-independent Nucleosome Assembly Negative Regulation Of Stress-activated MAPK Cascade Cellular Response To DsRNA Regulation Of Phosphorylation Heme Metabolic Process Regulation Of Centrosome Duplication Regulation Of Phosphorus Metabolic Process Regulation Of Centrosome Cycle Centromere Complex Assembly Porphyrin-containing Compound Metabolic Process Centrosome Cycle ATP-dependent Chromatin Remodeling Cell Aging Response To DsRNA Positive Regulation Of Translation Tetrapyrrole Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Centrosome Organization Regulation Of Protein Metabolic Process Microtubule Organizing Center Organization Nucleosome Assembly Regulation Of Catalytic Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Immune Response Chromatin Assembly Nucleosome Organization Regulation Of Microtubule Cytoskeleton Organization Chromatin Assembly Or Disassembly Negative Regulation Of MAPK Cascade Negative Regulation Of Cytoskeleton Organization Protein-DNA Complex Assembly	Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Acute-phase Response Leukocyte Migration Platelet Degranulation Acute Inflammatory Response Regulation Of Growth Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Blood Coagulation, Intrinsic Pathway Phosphatidylinositol-3-phosphate Biosynthetic Process Insulin Receptor Signaling Pathway Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Defense Response Regulation Of Developmental Growth Response To Insulin Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Response To Stress Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Response To Organonitrogen Compound Exocytosis Cell Migration Regulation Of Cell Growth T Cell Costimulation Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Phosphatidylinositol Phosphorylation Positive Regulation Of Reactive Oxygen Species Metabolic Process Lipid Phosphorylation Response To Hormone Extracellular Matrix Disassembly Hypomethylation Of CpG Island Maintenance Of Mitochondrion Location Negative Regulation Of Complement Activation, Lectin Pathway Regulation Of Multicellular Organism Growth Inflammatory Response Anatomical Structure Formation Involved In Morphogenesis
Tagcloud ?			2nh2 2oh amide aminomethylenebisphosphonate atom azido bisphosphonate bisphosphonates ch2 competitively constructing differing hydrolytic hydrophilic inorganic labelling nc nh2 photoactivatable photoaffinity po3 pocket ppase ppases ppi proton pumping pyrophosphatases vacuoles
Tagcloud (Difference) ?			2nh2 2oh amide aminomethylenebisphosphonate atom azido bisphosphonate bisphosphonates ch2 competitively constructing differing hydrolytic hydrophilic inorganic labelling nc nh2 photoactivatable photoaffinity po3 pocket ppase ppases ppi proton pumping pyrophosphatases vacuoles
Tagcloud (Intersection) ?