AMBP

Gene Name		alpha-1-microglobulin/bikunin precursor
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding Calcium Channel Inhibitor Activity IgA Binding Heme Binding Small Molecule Binding Protein Homodimerization Activity Calcium Oxalate Binding
	Biological Process	Receptor-mediated Endocytosis Cell Adhesion Female Pregnancy Negative Regulation Of Endopeptidase Activity Viral Process Protein-chromophore Linkage Protein Catabolic Process Heme Catabolic Process Negative Regulation Of JNK Cascade Negative Regulation Of Immune Response
Pathways		Scavenging of heme from plasma
Drugs		Human Serum Albumin Serum albumin iodonated
Diseases
GWAS
Protein-protein Interactions		12 interactors: A2M ALB COX8A DAAM1 ENO1 F2 FHL3 FN1 GRB2 PIK3CA PIK3R3 STAT3
Entrez ID		259
HPRD ID		01467
Ensembl ID		ENSG00000106927
Uniprot IDs		P02760
PDB IDs		1BIK 3QKG 4ES7
Enriched GO Terms of Interacting Partners?		Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Acute-phase Response Leukocyte Migration Platelet Degranulation Acute Inflammatory Response Regulation Of Growth Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Blood Coagulation, Intrinsic Pathway Phosphatidylinositol-3-phosphate Biosynthetic Process Insulin Receptor Signaling Pathway Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Defense Response Regulation Of Developmental Growth Response To Insulin Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Response To Stress Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Response To Organonitrogen Compound Exocytosis Cell Migration Regulation Of Cell Growth T Cell Costimulation Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Phosphatidylinositol Phosphorylation Positive Regulation Of Reactive Oxygen Species Metabolic Process Lipid Phosphorylation Response To Hormone Extracellular Matrix Disassembly Hypomethylation Of CpG Island Maintenance Of Mitochondrion Location Negative Regulation Of Complement Activation, Lectin Pathway Regulation Of Multicellular Organism Growth Inflammatory Response Anatomical Structure Formation Involved In Morphogenesis
Tagcloud ?		2nh2 2oh amide aminomethylenebisphosphonate atom azido bisphosphonate bisphosphonates ch2 competitively constructing differing hydrolytic hydrophilic inorganic labelling nc nh2 photoactivatable photoaffinity po3 pocket ppase ppases ppi proton pumping pyrophosphatases vacuoles