TMEM174 and PLLP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM174	PLLP
Description		transmembrane protein 174	plasmolipin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Apical Plasma Membrane	Golgi Apparatus Plasma Membrane Membrane Apical Plasma Membrane Myelin Sheath Compact Myelin Membrane Raft
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Myelin Sheath Identical Protein Binding
	Biological Process	Phosphate Ion Homeostasis	Monoatomic Ion Transport Regulation Of Endocytosis Myelin Assembly Myelination Regulation Of Transcytosis
Pathways
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 29403010) Eyebrow thickness ( 26926045) Hemoglobin levels ( 33491795) Monobrow ( 27182965) Monobrow thickness ( 26926045) Renal function-related traits (BUN) ( 22797727)	HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 28552196) Sleep duration ( 23728906) Systemic lupus erythematosus ( 28714469)
Interacting Genes		11 interacting genes: BAG3 CACNB2 CMTM7 CYSRT1 EMD KRT31 KRT34 MAL PLLP SEC22A SGTA	57 interacting genes: AQP6 BCL2L13 BIK CCR2 CD164L2 CLDN14 CLEC12B CLEC2D CRB3 CREB3 CYB5R3 CYSRT1 DRD2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FKBP7 FNDC9 FRS3 GOLT1A GPR35 GPX8 GRN HOXA1 HTR2B KCNJ6 KRT34 KRTAP10-1 KRTAP9-2 LHFPL5 LMNA MC4R MFF MMP14 MS4A12 OPRL1 PACC1 PGRMC2 PTAFR RNF122 SAR1A SLC10A6 SLC35H1 STING1 SYPL2 TIGIT TMEM14B TMEM167B TMEM174 TMPPE TMPRSS2 TNFSF14 TRIM59 VMA21 ZDHHC15
Entrez ID		134288	51090
HPRD ID		14432	11854
Ensembl ID		ENSG00000164325	ENSG00000102934
Uniprot IDs		Q8WUU8	Q9Y342
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Myelin Sheath Positive Regulation Of Protein Export From Nucleus Epidermis Development Regulation Of Protein Export From Nucleus Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels Membrane Depolarization During Atrial Cardiac Muscle Cell Action Potential Cellular Localization Positive Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved In Cardiac Muscle Cell Action Potential TMEM240-body Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Intracellular Protein Transport Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Protein Insertion Into Plasma Membrane Myelination Axon Ensheathment Membrane Raft Polarization Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Protein Insertion Into Membrane TRC Complex Regulation Of Transcytosis B-1a B Cell Differentiation Regulation Of Nucleocytoplasmic Transport Protein Localization To Paranode Region Of Axon BAT3 Complex Binding Compact Myelin B-1 B Cell Differentiation Membrane Depolarization During AV Node Cell Action Potential Supramolecular Fiber Organization Peptidase Activator Activity Involved In Apoptotic Process Positive Regulation Of Aggrephagy Positive Regulation Of Intracellular Transport Localization Within Membrane Photoreceptor Ribbon Synapse Regulation Of Intracellular Protein Transport Developmental Process Intermediate Filament Membrane Raft Distribution Negative Regulation Of ERAD Pathway Chaperone-mediated Autophagy Negative Regulation Of Protein Targeting To Mitochondrion Aggresome Assembly Cortical Endoplasmic Reticulum Membrane Raft Localization Negative Regulation Of Establishment Of Protein Localization To Mitochondrion	Membrane Endoplasmic Reticulum PH-gated Chloride Channel Activity Protein Binding Regulation Of Behavior Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
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