GRPEL2 and HSPA4

Number of citations of the paper that reports this interaction (PMID 9694873)
6

Data Source:
HPRD (in vitro)

		GRPEL2	HSPA4
Gene Name		GrpE-like 2, mitochondrial (E. coli)	heat shock 70kDa protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Homodimerization Activity Unfolded Protein Binding Chaperone Binding	ATP Binding
	Biological Process	Protein Folding Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Regulation Of Catalytic Activity	Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Chaperone-mediated Protein Complex Assembly
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: HSPA4	58 interactors: AGTRAP APPBP2 BAG1 BAG2 BAG5 BRMS1 CALM1 CD40 CDC73 CDKN2A CSNK1A1 CSNK2A1 DDIT4 DNAJB1 DUSP1 EGFR ESR1 FANCC FES FKBP4 GATA1 GRPEL2 GSK3B GZMA HAP1 HDAC3 HNRNPD HSPBP1 IKBKG KPNA2 KRT18 MAPT NFKB1 NR3C2 OLR1 PHLDA1 PPP1CA PRKCB PRKCD PRKCG PRSS23 PSMD10 RAF1 REL RELA SMAD3 SOD1 ST13 STIP1 STUB1 SUGT1 TERT TIMM44 TOMM40 TRAF6 TTC1 UBE2L3 UBE3A
Entrez ID		134266	3308
HPRD ID		17079	09025
Ensembl ID		ENSG00000164284
Uniprot IDs		B4DFA6 Q8TAA5	P34932
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Import Into Mitochondrial Outer Membrane Chaperone-mediated Protein Complex Assembly Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Mitochondrial Membrane Organization Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Response To Unfolded Protein Mitochondrial Transport Protein Import Establishment Of Protein Localization To Membrane Cellular Protein Complex Assembly Establishment Of Protein Localization To Organelle Protein Localization To Membrane Mitochondrion Organization Protein Targeting	Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cell Death Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Protein Metabolic Process Response To Organic Substance Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Cell Death Death Neurotrophin Signaling Pathway Positive Regulation Of Cellular Metabolic Process Regulation Of Signaling Negative Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Cellular Response To Growth Factor Stimulus Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Process Response To Growth Factor Cellular Response To Stimulus Programmed Cell Death Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Negative Regulation Of Signal Transduction Cellular Metabolic Process Signaling Response To Stimulus Cell Communication Regulation Of Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Cell Death Cellular Protein Metabolic Process Signal Transduction Regulation Of Protein Phosphorylation Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death
Tagcloud ?			competence cumulus damaged domestic fertility hfs2 hsf hsf1 hsp110 hsp40 hsp90a hsp90b hsph1 hsps machinery oocyte oocytes operational ovaries ovary pig preserve sows summer unexpectedly warm winter
Tagcloud (Difference) ?			competence cumulus damaged domestic fertility hfs2 hsf hsf1 hsp110 hsp40 hsp90a hsp90b hsph1 hsps machinery oocyte oocytes operational ovaries ovary pig preserve sows summer unexpectedly warm winter
Tagcloud (Intersection) ?