CTNND1 and FER

Number of citations of the paper that reports this interaction (PMID 12640114)
74

Data Source:
HPRD (in vivo)

		CTNND1	FER
Gene Name		catenin (cadherin-associated protein), delta 1	fer (fps/fes related) tyrosine kinase
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Zonula Adherens Lamellipodium Growth Cone Midbody Dendritic Spine Synapse Extracellular Vesicular Exosome	Nuclear Chromatin Nucleus Cytoplasm Cytosol Cell Cortex Actin Cytoskeleton Microtubule Cytoskeleton Lamellipodium Cell Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Receptor Binding Protein Binding Protein Kinase Binding Cadherin Binding	Actin Binding Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Epidermal Growth Factor Receptor Binding Protein Binding ATP Binding Protein Phosphatase 1 Binding Lipid Binding Rab GTPase Binding Protein Kinase Binding Gamma-catenin Binding Cadherin Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Adhesion Brain Development Wnt Signaling Pathway Single Organismal Cell-cell Adhesion Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Regulation Of Protein Phosphorylation Protein Phosphorylation Chemotaxis Cell Adhesion Cell Proliferation Positive Regulation Of Cell Proliferation Regulation Of Lamellipodium Assembly Regulation Of Fibroblast Migration Peptidyl-tyrosine Phosphorylation Cytokine-mediated Signaling Pathway Cell Differentiation Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Response To Lipopolysaccharide Cellular Response To Insulin Stimulus Negative Regulation Of Mast Cell Activation Involved In Immune Response Substrate Adhesion-dependent Cell Spreading Cellular Response To Reactive Oxygen Species Extracellular Matrix-cell Signaling Intracellular Signal Transduction Cellular Response To Macrophage Colony-stimulating Factor Stimulus Response To Platelet-derived Growth Factor Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Peptidyl-tyrosine Autophosphorylation Fc-epsilon Receptor Signaling Pathway Kit Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Proliferation Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Mast Cell Degranulation Cell-cell Adhesion Mediated By Cadherin Innate Immune Response Protein Autophosphorylation Platelet-derived Growth Factor Receptor Signaling Pathway Diapedesis Positive Regulation Of NF-kappaB Transcription Factor Activity Interleukin-6-mediated Signaling Pathway
Pathways		Cell junction organization Cell-cell junction organization Signaling by VEGF Adherens junctions interactions VEGFR2 mediated vascular permeability VEGFA-VEGFR2 Pathway	Signaling by SCF-KIT
Drugs
Diseases
GWAS			Adiponectin levels ( 21700879) Height ( 20881960)
Protein-Protein Interactions		26 interactors: ACTA1 APP CDH1 CDH24 CDH3 CDH5 COL17A1 CTTN EGFR ERBB2IP FER GRIK2 GSK3B JUP KCTD6 LCK MTNR1B MUC1 PSEN1 PTPN6 PTPRJ PTPRM SNCA SRC YWHAG ZBTB33	14 interactors: CALM1 CDH1 CTNNB1 CTNND1 CTTN EGFR ERBB2 ERBB3 IRS1 JAK1 JUP STAT3 TMF1 YWHAB
Entrez ID		1500	2241
HPRD ID		03026	01491
Ensembl ID		ENSG00000198561
Uniprot IDs		C9JZR2 O60716	P16591 Q05DA5
PDB IDs		3L6X 3L6Y	2KK6
Enriched GO Terms of Interacting Partners?		Cell Adhesion Adherens Junction Organization Regulation Of Signaling Single Organismal Cell-cell Adhesion Regulation Of Signal Transduction Regulation Of Cellular Localization Regulation Of Intracellular Transport Cellular Response To Organonitrogen Compound Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Junction Assembly Cell-cell Junction Organization Locomotion Cellular Response To Stimulus Regulation Of Phosphorylation Regulation Of Protein Phosphorylation Regulation Of Cellular Amino Acid Metabolic Process Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Negative Regulation Of Protein Metabolic Process Signaling Negative Regulation Of Signaling Enzyme Linked Receptor Protein Signaling Pathway Cell Communication Regulation Of ERBB Signaling Pathway Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Cellular Ketone Metabolic Process Signal Transduction Regulation Of Protein Kinase Activity Response To Drug Programmed Cell Death Cell Death Death Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Developmental Process Negative Regulation Of Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Response To Mechanical Stimulus Anatomical Structure Development Response To Organonitrogen Compound Response To External Stimulus Regulation Of Apoptotic Process Cell Migration Regulation Of Cell Proliferation Positive Regulation Of Intracellular Transport	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signaling Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Response To Organic Substance Epidermal Growth Factor Receptor Signaling Pathway Defense Response ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Adherens Junction Organization Cellular Response To Indole-3-methanol Developmental Process System Development Fc-epsilon Receptor Signaling Pathway Cellular Response To Organonitrogen Compound Innate Immune Response Response To Organonitrogen Compound Fc Receptor Signaling Pathway Regulation Of Immune System Process Regulation Of Immune Response Multicellular Organismal Development Positive Regulation Of Transferase Activity Anatomical Structure Development Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Regulation Of Cellular Localization Organ Development Glial Cell Differentiation Immune Response-regulating Cell Surface Receptor Signaling Pathway Nervous System Development Cell Surface Receptor Signaling Pathway Cell Junction Assembly Positive Regulation Of Transport Cellular Localization Cell-cell Junction Organization Locomotion Positive Regulation Of Signal Transduction Immune Response-regulating Signaling Pathway Response To Stress Gliogenesis Immune Response Positive Regulation Of Kinase Activity Positive Regulation Of Phosphorylation
Tagcloud ?		abi1 atlas bitbucket ccnd3 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript	amongst ark axl cdnas compartment compartments consequence contaminated dissect exclusively fresh freshly fyn hemopoietic immortalized mesodermal notion origin preparation ptk repertoire sequenced tec thymic thymocytes thymus tsc tyro ufo
Tagcloud (Difference) ?		abi1 atlas bitbucket ccnd3 doi driver drivers dx fbln2 figshare hindered http https identifies implies isoform ktsp m9 mitf myh11 org pparg prdm1 ralgds regulatorygenomicsupf signatures splicing switches transcript	amongst ark axl cdnas compartment compartments consequence contaminated dissect exclusively fresh freshly fyn hemopoietic immortalized mesodermal notion origin preparation ptk repertoire sequenced tec thymic thymocytes thymus tsc tyro ufo
Tagcloud (Intersection) ?