COL13A1 and ITGA1

Number of citations of the paper that reports this interaction (PMID 10713152)
23

Data Source:
HPRD (in vivo)

		COL13A1	ITGA1
Gene Name		collagen, type XIII, alpha 1	integrin, alpha 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Type XIII Trimer Endoplasmic Reticulum Lumen Plasma Membrane Cell-cell Junction	Acrosomal Vesicle Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Membrane Integrin Alpha1-beta1 Complex Neuron Projection Perikaryon Membrane Raft Basal Part Of Cell Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Heparin Binding	Receptor Binding Protein Binding Collagen Binding Protein Phosphatase Binding Metal Ion Binding Collagen Binding Involved In Cell-matrix Adhesion
	Biological Process	Morphogenesis Of A Branching Structure Endochondral Ossification Cell-matrix Adhesion Single Organismal Cell-cell Adhesion Extracellular Matrix Disassembly Cell Differentiation Extracellular Matrix Organization Collagen Catabolic Process	Activation Of MAPK Activity Muscle Contraction Cell-matrix Adhesion Integrin-mediated Signaling Pathway Axon Guidance Blood Coagulation Negative Regulation Of Cell Proliferation Extracellular Matrix Organization Neutrophil Chemotaxis Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vasodilation Positive Regulation Of Neuron Apoptotic Process Cellular Extravasation
Pathways		Collagen formation Collagen degradation Integrin cell surface interactions Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix	Platelet Adhesion to exposed collagen CHL1 interactions Axon guidance Laminin interactions Semaphorin interactions Other semaphorin interactions Smooth Muscle Contraction L1CAM interactions Integrin cell surface interactions
Drugs
Diseases
GWAS		Non-alcoholic fatty liver disease histology (lobular) ( 20708005) Parkinson's disease ( 23793441)	Alzheimer's disease biomarkers ( 23419831) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Pulmonary function ( 21946350) Pulmonary function (interaction) ( 23284291) Response to platinum-based agents ( 22020760)
Protein-Protein Interactions		6 interactors: FN1 HSPG2 ITGA1 NID1 NID2 SPARC	10 interactors: AUP1 BIN1 COL13A1 COL8A1 ITGB1 LAMA1 MATN1 PTPN2 SHARPIN TLN1
Entrez ID		1305	3672
HPRD ID		00383	01892
Ensembl ID		ENSG00000197467
Uniprot IDs		Q5TAT6	P56199
PDB IDs			1PT6 1QC5 1QCY 2L8S 4A0Q
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Cell-matrix Adhesion Cell-substrate Adhesion Extracellular Matrix Disassembly Basement Membrane Organization Cell Adhesion Blood Coagulation Hemostasis Platelet Degranulation Regulation Of Body Fluid Levels Wound Healing Response To Wounding System Development Cardiovascular System Development Calcium-independent Cell-matrix Adhesion Platelet Activation Leukocyte Migration Bone Development Multicellular Organismal Development Anatomical Structure Development Ossification Response To L-ascorbic Acid Angiogenesis Exocytosis Integrin Activation Response To Gravity Developmental Process Positive Regulation Of Phosphoprotein Phosphatase Activity Glomerular Basement Membrane Development Blood Vessel Morphogenesis Regulation Of Cell Morphogenesis Secretion By Cell Heart Development Blood Vessel Development Response To Lead Ion Vasculature Development Cellular Extravasation Response To External Stimulus	Cell Differentiation Extracellular Matrix Organization Extracellular Structure Organization System Development Multicellular Organismal Development Anatomical Structure Development Cell Adhesion Developmental Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Organ Development Single Organismal Cell-cell Adhesion Regulation Of Cell Adhesion Anatomical Structure Morphogenesis Cell Morphogenesis Involved In Differentiation Tissue Development Collagen Catabolic Process Cellular Component Assembly Organ Morphogenesis Axon Guidance Negative Regulation Of Interleukin-4-mediated Signaling Pathway Negative Regulation Of Prolactin Signaling Pathway Negative Regulation Of Positive Thymic T Cell Selection Negative Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Negative Regulation Of Tyrosine Phosphorylation Of Stat6 Protein Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway Growth Plate Cartilage Chondrocyte Morphogenesis Negative Regulation Of Interleukin-2-mediated Signaling Pathway Collagen Metabolic Process Cell Morphogenesis Blood Vessel Morphogenesis Endochondral Bone Morphogenesis Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Endocytosis B Cell Differentiation Negative Regulation Of Inflammatory Response Blood Vessel Development Nervous System Development Lipid Tube Assembly Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Negative Regulation Of Interleukin-6-mediated Signaling Pathway Positive Regulation Of Cell-substrate Adhesion Cell-cell Junction Assembly Axonogenesis Vasculature Development Bone Morphogenesis Axon Development Formation Of Primary Germ Layer
Tagcloud ?		alt anthropometric apoc3 cms consent corrections efcab4b infiltration iu nafld ncan obtaining parvb patatin pnpla3 pzp rs2073080 rs2143571 rs2228603 rs2854117 rs343062 rs6487679 rs6591182 rs738409 samm50 sequenom snps transaminase triglyceride
Tagcloud (Difference) ?		alt anthropometric apoc3 cms consent corrections efcab4b infiltration iu nafld ncan obtaining parvb patatin pnpla3 pzp rs2073080 rs2143571 rs2228603 rs2854117 rs343062 rs6487679 rs6591182 rs738409 samm50 sequenom snps transaminase triglyceride
Tagcloud (Intersection) ?