MOB3A and LATS2

Number of citations of the paper that reports this interaction (PMID 19739119)
11

Data Source:
BioGRID (pull down)

		MOB3A	LATS2
Gene Name		MOB kinase activator 3A	large tumor suppressor kinase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Cytosol
	Molecular Function	Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process		G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Hormone-mediated Signaling Pathway Keratinocyte Differentiation Cellular Protein Localization Hippo Signaling Intracellular Signal Transduction Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Organ Growth Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP LATS1 LATS2 NEDD4 NEDD4L	19 interactors: ABL1 AJUBA AMOT AURKB CDK2 CDKN1A CHEK1 CHEK2 CTNNB1 DYRK1A MOB3A MOB3B MOB3C MOB4 SNAI1 STK3 TAZ YAP1 YWHAG
Entrez ID		126308	26524
HPRD ID		17583	07277
Ensembl ID		ENSG00000172081	ENSG00000150457
Uniprot IDs		Q96BX8	Q9NRM7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Sodium Ion Transport Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Hippo Signaling Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Negative Regulation Of Signaling Positive Regulation Of Protein Metabolic Process Regulation Of Signaling Negative Regulation Of Transport Neuromuscular Junction Development Cellular Protein Modification Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Keratinocyte Differentiation Regulation Of Synapse Structure Or Activity Negative Regulation Of Ion Transport Cellular Response To Organic Substance Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Negative Regulation Of Protein Serine/threonine Kinase Activity Epidermal Cell Differentiation Hormone-mediated Signaling Pathway Negative Regulation Of Catalytic Activity Regulation Of Ion Transmembrane Transporter Activity Regulation Of Kinase Activity Regulation Of Transmembrane Transporter Activity Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Negative Regulation Of Protein Metabolic Process Cellular Localization Protein Polyubiquitination Synapse Organization Signal Transduction Regulation Of Cell Cycle Regulation Of Cellular Response To Growth Factor Stimulus Collateral Sprouting In Absence Of Injury	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Cell Cycle Hippo Signaling Regulation Of Cellular Component Organization Positive Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle Mitotic Cell Cycle Phase Transition Regulation Of Protein Metabolic Process Cell Cycle Phase Transition DNA Damage Induced Protein Phosphorylation Positive Regulation Of Stem Cell Differentiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Developmental Process Intrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Regulation Of Nephron Tubule Epithelial Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Mitotic Cell Cycle Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Protein Autophosphorylation Cell Cycle Checkpoint Negative Regulation Of Signaling Negative Regulation Of Kinase Activity Regulation Of Metabolic Process Regulation Of Gene Expression Signal Transduction In Response To DNA Damage Regulation Of Nitrogen Compound Metabolic Process Regulation Of Signaling Regulation Of Cell Cycle Process Protein Phosphorylation Phosphorylation Intracellular Signal Transduction Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Regulation Of Response To DNA Damage Stimulus Histone Phosphorylation Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Proliferation Cellular Response To Radiation Apoptotic Signaling Pathway
Tagcloud ?			address approach bioinformatics carried challenging contribute damage discovery efficiently especially genome hlats1 lats1 mutations numerous opportunities powerful predicted projects putative question regulators silico sort support suppressor suppressors understood unprecedented
Tagcloud (Difference) ?			address approach bioinformatics carried challenging contribute damage discovery efficiently especially genome hlats1 lats1 mutations numerous opportunities powerful predicted projects putative question regulators silico sort support suppressor suppressors understood unprecedented
Tagcloud (Intersection) ?