TPST2 and GOLPH3

Number of citations of the paper that reports this interaction (PubMedID 34473204)
68

Data Source:
BioGRID (pull down)

		TPST2	GOLPH3
Description		tyrosylprotein sulfotransferase 2	golgi phosphoprotein 3
Image
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Golgi Lumen Trans-Golgi Network Membrane	Golgi Membrane Mitochondrion Mitochondrial Intermembrane Space Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Membrane Golgi Cisterna Golgi Cisterna Membrane
	Molecular Function	Protein-tyrosine Sulfotransferase Activity Transferase Activity Protein Homodimerization Activity	Protein Binding Lipid Binding Enzyme Binding Phosphatidylinositol-4-phosphate Binding Cargo Adaptor Activity
	Biological Process	Peptidyl-tyrosine Sulfation Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Prevention Of Polyspermy	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Glycoprotein Biosynthetic Process Protein Secretion Gene Expression Regulation Of Mitochondrion Organization Protein Transport Cell Migration Lamellipodium Assembly Positive Regulation Of TOR Signaling Golgi To Plasma Membrane Protein Transport Negative Regulation Of Apoptotic Process Protein Retention In Golgi Apparatus Golgi Vesicle Budding Positive Regulation Of Protein Secretion Leukocyte Tethering Or Rolling Cell Adhesion Molecule Production Cellular Response To Rapamycin Golgi Ribbon Formation Asymmetric Golgi Ribbon Formation Protein Targeting To Golgi Apparatus
Pathways		Cytosolic sulfonation of small molecules Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation Defective F8 sulfation at Y1699 Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Blood protein levels ( 30072576) Metabolite levels ( 23823483)	Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: CCR1 CCR8 CMKLR1 CMKLR2 GOLPH3 GOLPH3L SELPLG	23 interacting genes: ARL6IP1 B4GALT4 C1GALT1 CANT1 DIPK2A EBAG9 EXT1 FAM20B FAM3C GALNT2 GALNT6 GALNT7 GCNT1 GLG1 GLT8D1 GOLIM4 GOLM2 MAN1B1 MGAT2 PGAP4 POMGNT1 TPST1 TPST2
Entrez ID		8459	64083
HPRD ID		07217	11007
Ensembl ID		ENSG00000128294	ENSG00000113384
Uniprot IDs		O60704	Q9H4A6
PDB IDs		3AP1 3AP2 3AP3	3KN1
Enriched GO Terms of Interacting Partners?		Chemokine Receptor Activity Adipokinetic Hormone Binding Adipokinetic Hormone Receptor Activity Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Chemokine-mediated Signaling Pathway Golgi Cisterna G Protein-coupled Receptor Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Leukocyte Tethering Or Rolling C-C Chemokine Binding C-C Chemokine Receptor Activity Leukocyte Adhesion To Vascular Endothelial Cell Phosphatidylinositol-4-phosphate Binding Vesicle Budding From Membrane Golgi To Plasma Membrane Protein Transport G Protein-coupled Receptor Signaling Pathway Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Cell Adhesion Cell Migration Chemotaxis Leukocyte Cell-cell Adhesion Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Locomotion Golgi Cisterna Membrane Cell Motility Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Chemotaxis Chemokine (C-C Motif) Ligand 5 Binding Chemokine (C-C Motif) Ligand 7 Binding Leukocyte Adhesive Activation Post-Golgi Vesicle-mediated Transport Asymmetric Golgi Ribbon Formation Golgi Organization Response To Cytokine Response To Peptide Cell Adhesion Molecule Production Cellular Response To Rapamycin Vesicle-mediated Transport To The Plasma Membrane Regulation Of Mononuclear Cell Migration Positive Regulation Of Chemotaxis Positive Regulation Of Protein Secretion Positive Regulation Of Leukocyte Migration Signaling Membrane Protein Retention In Golgi Apparatus	Golgi Apparatus Golgi Membrane Glycoprotein Metabolic Process Glycosyltransferase Activity Glycoprotein Biosynthetic Process Protein Glycosylation Macromolecule Glycosylation Carbohydrate Derivative Metabolic Process Glycosylation Carbohydrate Derivative Biosynthetic Process Protein O-linked Glycosylation Protein O-linked Glycosylation Via N-acetyl-galactosamine Transferase Activity Macromolecule Biosynthetic Process Protein Modification Process Protein Metabolic Process Membrane Polypeptide N-acetylgalactosaminyltransferase Activity Proteoglycan Biosynthetic Process Protein-tyrosine Sulfotransferase Activity Carbohydrate Binding Proteoglycan Metabolic Process Macromolecule Metabolic Process Manganese Ion Binding Golgi Cisterna Membrane Carbohydrate Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Acetylglucosaminyltransferase Activity UDP-glycosyltransferase Activity Leukocyte Tethering Or Rolling Golgi Lumen Leukocyte Adhesion To Vascular Endothelial Cell Viral Protein Processing Basement Membrane Organization Bone Morphogenesis Lymphocyte Adhesion To Endothelial Cell Of High Endothelial Venule Perichondral Bone Morphogenesis Sweat Gland Development Smoothened Signaling Pathway Involved In Lung Development Golgi Stack Alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase Activity Peptidyl-tyrosine Sulfation Trans-Golgi Network Protein Homodimerization Activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase Activity Mesenchymal Cell Differentiation Involved In Bone Development Stomach Development Heparan Sulfate N-acetylglucosaminyltransferase Activity Leukocyte Cell-cell Adhesion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?