DCUN1D3 and CUL4B

Number of citations of the paper that reports this interaction (PMID 23201271)
5

Data Source:
BioGRID (pull down)

		DCUN1D3	CUL4B
Gene Name		DCN1, defective in cullin neddylation 1, domain containing 3	cullin 4B
Image
Gene Ontology Annotations	Cellular Component	Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Plasma Membrane Cul4B-RING E3 Ubiquitin Ligase Complex Extracellular Vesicular Exosome
	Molecular Function	Molecular_function	Damaged DNA Binding Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Response To UV-C Response To Gamma Radiation Negative Regulation Of Cell Growth Positive Regulation Of Apoptotic Process	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Histone H2A Monoubiquitination Positive Regulation Of Protein Catabolic Process UV-damage Excision Repair Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CUL4A CUL4B CUL5 UBE2M	22 interactors: AHR APP AR CAND1 COMMD1 DCUN1D1 DCUN1D3 DCUN1D4 DCUN1D5 DDB1 DDB2 DTL ESR1 KPNA2 KPNA4 KPNB1 NEDD8 RBX1 RNF7 SALL2 SIN3A UBC
Entrez ID		123879	8450
HPRD ID		14660	02251
Ensembl ID			ENSG00000158290
Uniprot IDs		Q8IWE4	Q13620
PDB IDs		4GBA	2DO7 4A0C 4A0L 4A64
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Positive Regulation Of Mitotic Cell Cycle Regulation Of Nucleotide-excision Repair Cellular Macromolecule Catabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cell Cycle Arrest Regulation Of Cell Cycle G1/S Transition Of Mitotic Cell Cycle Cellular Protein Modification Process Intrinsic Apoptotic Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Cell Cycle Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Proteolysis UV-damage Excision Repair Cellular Protein Metabolic Process Negative Regulation Of Granulocyte Differentiation Apoptotic Signaling Pathway Protein Neddylation Catabolic Process Regulation Of Mitotic Cell Cycle Regulation Of DNA Damage Checkpoint Histone H2A Monoubiquitination Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process Histone H2A Ubiquitination Protein Metabolic Process Viral Process Histone Monoubiquitination DNA Repair Negative Regulation Of Cell Proliferation Mitotic Cell Cycle Process Mitotic Cell Cycle Histone Ubiquitination Cellular Response To Stimulus	Protein Modification By Small Protein Conjugation Protein Monoubiquitination Protein Neddylation Protein Ubiquitination Intracellular Receptor Signaling Pathway NLS-bearing Protein Import Into Nucleus Regulation Of Transcription From RNA Polymerase II Promoter DNA Metabolic Process Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Response To UV Cellular Macromolecule Catabolic Process Response To Light Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly UV-damage Excision Repair Positive Regulation Of Transcription From RNA Polymerase II Promoter Prostate Gland Development Response To Abiotic Stimulus Nucleobase-containing Compound Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Response To Radiation Regulation Of Cell Cycle Phase Transition Histone H2A Monoubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Modification-dependent Protein Catabolic Process Cellular Response To Stimulus Histone H2A Ubiquitination Cellular Nitrogen Compound Metabolic Process Positive Regulation Of DNA-templated Transcription, Initiation Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Protein Catabolic Process Nucleotide-excision Repair, DNA Damage Removal Cellular Response To Organic Substance Rhythmic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Import Into Nucleus Histone Monoubiquitination DNA Repair Nuclear Import Regulation Of DNA-templated Transcription, Initiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Catabolic Process Copper Ion Homeostasis Regulation Of Apoptotic Process
Tagcloud ?			absent alleviate assemble augmented blunted dampening depleted downregulated drives driving e3 ectopic exacerbate feedback greatly h2o2 ligases loop mildly negatively nhfs oxidative proteosomal replicative ros senescence senescent stressed ubiquitination
Tagcloud (Difference) ?			absent alleviate assemble augmented blunted dampening depleted downregulated drives driving e3 ectopic exacerbate feedback greatly h2o2 ligases loop mildly negatively nhfs oxidative proteosomal replicative ros senescence senescent stressed ubiquitination
Tagcloud (Intersection) ?