DCUN1D3

Description		defective in cullin neddylation 1 domain containing 3
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding
	Biological Process	Response To UV-C Response To Gamma Radiation Regulation Of Cell Cycle Process Negative Regulation Of Cell Growth Positive Regulation Of Apoptotic Process Protein Neddylation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Protein Neddylation Negative Regulation Of Protein Neddylation Positive Regulation Of Protein Neddylation
Pathways		Neddylation
Drugs
Diseases
GWAS		Hippocampal sclerosis ( 25188341)
Interacting Genes		3 interacting genes: CUL2 CUL3 UBE2M
Entrez ID		123879
HPRD ID		14660
Ensembl ID		ENSG00000188215
Uniprot IDs		Q8IWE4
PDB IDs		4GBA
Enriched GO Terms of Interacting Partners?		Ubiquitin Ligase Complex Scaffold Activity Cullin-RING Ubiquitin Ligase Complex Ubiquitin-protein Transferase Activity Protein Modification By Small Protein Conjugation Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Post-translational Protein Modification Mitotic Cell Cycle Phase Transition Trophectodermal Cellular Morphogenesis Intrinsic Apoptotic Signaling Pathway Liver Morphogenesis Cell Cycle Phase Transition NEDD8 Conjugating Enzyme Activity Regulation Protein Catabolic Process At Postsynapse Postsynapse POZ Domain Binding Protein Modification Process Polar Microtubule NEDD8 Transferase Activity Ubiquitin Protein Ligase Binding Apoptotic Signaling Pathway Nuclear Protein Quality Control By The Ubiquitin-proteasome System Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Cleavage Fibroblast Apoptotic Process Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway Proteasomal Protein Catabolic Process Negative Regulation Of Rho Protein Signal Transduction Renal Sodium Ion Transport Positive Regulation Of Mitotic Sister Chromatid Separation Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Notch Binding Modification-dependent Protein Catabolic Process Contractile Actin Filament Bundle Assembly Anaphase-promoting Complex-dependent Catabolic Process Stress Fiber Assembly Positive Regulation Of Mitotic Metaphase/anaphase Transition COPII Vesicle Coating Protein Catabolic Process RNA Polymerase II Transcription Initiation Surveillance Renal Sodium Ion Absorption Glutamatergic Synapse Cul2-RING Ubiquitin Ligase Complex Ubiquitin-like Protein Transferase Activity Protein Neddylation Stem Cell Division Proteolysis Involved In Protein Catabolic Process Protein Metabolic Process Gland Morphogenesis
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