JDP2 and JUNB

Number of citations of the paper that reports this interaction (PMID 9154808)
109

Data Source:
HPRD (in vivo, in vitro)

		JDP2	JUNB
Gene Name		Jun dimerization protein 2	jun B proto-oncogene
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleoplasm
	Molecular Function	Chromatin Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Histone Deacetylation Negative Regulation Of Fat Cell Differentiation	Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Response To Light Stimulus Response To Mechanical Stimulus Gene Expression Osteoclast Differentiation Response To Progesterone Cellular Response To Hormone Stimulus Osteoblast Proliferation Response To Cytokine Response To Drug Response To Peptide Hormone Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Decidualization Response To Corticosterone Response To CAMP Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			Loss of Function of TGFBR2 in Cancer TGFBR2 MSI Frameshift Mutants in Cancer SMAD2/3 Phosphorylation Motif Mutants in Cancer Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer SMAD2/3 MH2 Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer Loss of Function of TGFBR1 in Cancer Generic Transcription Pathway Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Periodontal microbiota ( 22699663)
Protein-Protein Interactions		18 interactors: ATF2 CREBBP EP300 GTF2H1 HDAC1 HDAC4 HDAC5 HDAC6 IRF2BP1 JUN JUNB JUND KAT2B MAPK14 MAPK8 MAPK9 PGR SNW1	37 interactors: APLP2 ATF3 ATF4 BATF BATF2 BATF3 BCL6 BDNF BRCA1 C19orf68 DDIT3 EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG USP24 ZNF595
Entrez ID		122953	3726
HPRD ID		16360	01303
Ensembl ID		ENSG00000140044	ENSG00000171223
Uniprot IDs		Q8WYK2	P17275 Q5U079
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organic Substance Histone H3-K9 Modification Transcription From RNA Polymerase II Promoter Histone Modification DNA-templated Transcription, Initiation N-terminal Peptidyl-lysine Acetylation Nucleobase-containing Compound Metabolic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Notch Signaling Pathway Cellular Response To Organic Substance Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Metabolic Process Response To Abiotic Stimulus MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Rhythmic Process Regulation Of Viral Transcription Cellular Nitrogen Compound Metabolic Process MyD88-dependent Toll-like Receptor Signaling Pathway Histone H4 Deacetylation	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Organic Substance Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Protein Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Response To External Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Lipid Response To Mechanical Stimulus Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Response To Abiotic Stimulus Developmental Process Response To Corticosterone Response To Biotic Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Response To Mineralocorticoid Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		ap basal cloned contains dimerization direct extension feedback flanking given inhibits interestingly investigate jun key link loop nt oncogenic p53 primer promoter region repressed repressor start suppressor transcription transcriptional	accumulated amplified clones delay differentiate differentiative ectopic epo erythroid erythropoietin evaluating g418 grow heavy introduced lg modifies modify neither plasmacytoma proliferated proliferative providing responsive retrovirally stat5 tepc transduced varied
Tagcloud (Difference) ?		ap basal cloned contains dimerization direct extension feedback flanking given inhibits interestingly investigate jun key link loop nt oncogenic p53 primer promoter region repressed repressor start suppressor transcription transcriptional	accumulated amplified clones delay differentiate differentiative ectopic epo erythroid erythropoietin evaluating g418 grow heavy introduced lg modifies modify neither plasmacytoma proliferated proliferative providing responsive retrovirally stat5 tepc transduced varied
Tagcloud (Intersection) ?