JDP2 and IRF2BP1

Number of citations of the paper that reports this interaction (PubMedID 18671972)
0

Data Source:
BioGRID (pull down)

		JDP2	IRF2BP1
Description		Jun dimerization protein 2	interferon regulatory factor 2 binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Protein Homodimerization Activity Histone Deacetylase Binding Leucine Zipper Domain Binding Protein Heterodimerization Activity Histone Chaperone Activity Sequence-specific Double-stranded DNA Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Fat Cell Differentiation Negative Regulation Of Fat Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Protein Polyubiquitination Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Pseudoephedrine
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Appendicular lean mass ( 33097823) Basal cell carcinoma ( 31174203 33549134) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 24076602) Obesity-related traits ( 23251661) Periodontal microbiota ( 22699663)	Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851) Gallstone disease ( 30504769) HDL cholesterol levels ( 32203549) Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		22 interacting genes: ATF2 ATF4 CREB5 CREBBP DDIT3 EP300 GTF2H1 HDAC1 HDAC4 HDAC5 HDAC6 IRF2BP1 JUN JUNB JUND KAT2B MAPK14 MAPK8 MAPK9 PGR SNW1 TP53	9 interacting genes: ATF2 CEBPA IRF2 IRF9 JDP2 PCBD2 SMAD1 TGIF1 UBE2L3
Entrez ID		122953	26145
HPRD ID		16360	17159
Ensembl ID		ENSG00000140044	ENSG00000170604
Uniprot IDs		Q8WYK2	Q8IU81
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process Rhythmic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Stress Negative Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Chromatin Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Regulation Of Primary Metabolic Process Nucleus Nucleoplasm Regulation Of Macromolecule Metabolic Process Histone Deacetylase Binding Histone Deacetylase Activity, Hydrolytic Mechanism Response To Stress RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Cis-regulatory Region Binding Enzyme Binding Regulation Of Metabolic Process Epigenetic Regulation Of Gene Expression Protein Lysine Deacetylase Activity N-terminal Peptidyl-lysine Acetylation DNA-binding Transcription Factor Binding Intracellular Signaling Cassette Chromatin Binding Response To Nutrient Levels Histone Deacetylase Activity Positive Regulation Of Gene Expression	DNA-binding Transcription Factor Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cell Population Proliferation Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Sequence-specific Double-stranded DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding Regulation Of Primary Metabolic Process Leucine Zipper Domain Binding CAMP Response Element Binding Co-SMAD Binding Fat Cell Differentiation White Fat Cell Differentiation Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulator Complex DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Chromatin Binding Regulation Of Metabolic Process Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription Cis-regulatory Region Binding Positive Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Abducens Nucleus Development Hypoglossal Nucleus Development Protein Heterodimerization Activity Positive Regulation Of Osteoblast Differentiation Nucleobase-containing Compound Biosynthetic Process
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