| Name |
CLPTM1 regulator of GABA type A receptor forward trafficking |
solute carrier family 22 member 1 |
| Structure |
No pdb structure
|
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
None
|
|
| GWAS |
- Alzheimer's disease or family history of Alzheimer's disease ( 30617256
)
- Alzheimer's disease or HDL levels (pleiotropy) ( 30805717
)
- Apolipoprotein B levels ( 32203549
)
- Basal cell carcinoma ( 31174203
)
- Body mass index ( 26426971
)
- Body mass index (age>50) ( 26426971
)
- Body mass index x age interaction ( 26426971
)
- Body mass index x sex x age interaction (4df test) ( 26426971
)
- Carotid intima media thickness (maximum) ( 31801372
)
- Carotid intima media thickness (mean) ( 31801372
)
- Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321
)
- Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321
)
- Cerebrospinal AB1-42 levels in normal cognition ( 29274321
)
- Cerebrospinal fluid AB1-42 levels ( 29274321
)
- Cerebrospinal fluid p-tau levels ( 29274321
)
- Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321
)
- Cerebrospinal fluid t-tau levels ( 29274321
)
- Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321
)
- Hippocampal volume ( 29274321
)
- Hippocampal volume in Alzheimer's disease dementia ( 29274321
)
- Keratinocyte cancer (MTAG) ( 31174203
)
- LDL cholesterol levels ( 32203549
)
- Logical memory (delayed recall) ( 29274321
)
- Logical memory (immediate recall) ( 29274321
)
- Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659
)
|
- Apolipoprotein B levels ( 32203549
)
- Body mass index ( 26426971
)
- Body mass index (age>50) ( 26426971
)
- Body mass index x sex x age interaction (4df test) ( 26426971
)
- Essential hypertension (time to event) ( 32589924
)
- Gout ( 22179738
)
- HOMA-B (corrected for HOMA-IR) ( 30369944
)
- LDL cholesterol levels ( 32203549
)
- LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535
)
- LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535
)
- Lipoprotein (a) levels ( 26377243
)
- Liver enzyme levels (alkaline phosphatase) ( 33972514
)
- Liver enzyme levels (gamma-glutamyl transferase) ( 33972514
)
- Low density lipoprotein cholesterol levels ( 33339817
)
- Medication use (HMG CoA reductase inhibitors) ( 31015401
)
- Metabolic traits ( 21886157
)
- Prostate cancer ( 21743057
26034056
)
- Serum metabolite levels ( 33031748
23093944
)
- Triglyceride levels ( 32203549
)
- Urinary metabolite levels in chronic kidney disease ( 31959995
29545352
)
|
| Novel Interactors |
None recorded
|
3 novel interactors:
ARID5B
GRM3
OS9
|
| Interacting Genes |
8 interacting genes:
CCR2
CCR4
F2RL1
FZD7
LINC00839
SLC22A1
SLC22A2
UNC93B1
|
27 interacting genes:
ALDOA
CAPN1
CCL2
CD63
CD9
CERS2
CHST12
CLPTM1
CYSTM1
FIS1
FXYD2
GHITM
KRTCAP2
LAPTM4A
LAPTM4B
MUC1
PDZK1IP1
POU2AF1
SERP1
SLC25A11
SMIM24
SMIM3
SPP1
TMBIM4
TMEM147
TMEM179B
VAPB
|
| Entrez ID |
1209 |
6580 |
| HPRD ID |
07544
|
04007
|
| Ensembl ID |
ENSG00000104853
|
ENSG00000175003
|
| Uniprot IDs |
A0A0S2Z3H2
O96005
|
O15245
|
| PDB IDs |
Not available
|
8ET6
8ET7
8ET8
8JTS
8JTT
8JTV
8JTW
8JTX
8JTY
8JTZ
8JU0
8SC1
8SC2
8SC3
8SC4
8SC6
|
| GO Terms Enriched among Interactors |
|
|