SLC22A1

Gene Name		solute carrier family 22 (organic cation transporter), member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	Acetylcholine Transmembrane Transporter Activity Dopamine Transmembrane Transporter Activity Norepinephrine Transmembrane Transporter Activity Protein Binding Secondary Active Organic Cation Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Protein Homodimerization Activity
	Biological Process	Neurotransmitter Transport Drug Transmembrane Transport Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Organic Cation Transport Quaternary Ammonium Group Transport Dopamine Transport Norepinephrine Transport Small Molecule Metabolic Process Epinephrine Transport Protein Homooligomerization Transmembrane Transport Ammonium Transmembrane Transport Acetate Ester Transport
Pathways		Na+/Cl- dependent neurotransmitter transporters Neurotransmitter Release Cycle Neurotransmitter Clearance In The Synaptic Cleft Organic cation transport Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Norepinephrine Neurotransmitter Release Cycle Abacavir transmembrane transport Organic cation/anion/zwitterion transport SLC-mediated transmembrane transport Abacavir transport and metabolism Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Metabolic traits ( 21886157) Prostate cancer ( 21743057)
Protein-protein Interactions		2 interactors: CERS2 POU2AF1
Entrez ID		6580
HPRD ID		04007
Ensembl ID		ENSG00000175003
Uniprot IDs		O15245
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		adopted agonists cation cml endocrine hence hoct1 imatinib improve killing leukaemia myeloid organic orphan peroxisome potentially ppar predictor pregnane proliferator pxr rank rar retinoid rxr transporter upregulated uptake wilcoxon